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NCT04415658 · ClinicalTrials.gov registry record · Phase 3
Intravenous Thyroxine for Heart-Eligible Organ Donors
A Phase 3 study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- Phase 3
- Development phase
- 838
- Enrollment target
NCT04415658: Completed Phase 3 study, sponsored by Washington University School of Medicine.
NCT04415658 is a Phase 3 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 838 participants, roughly in line with the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04415658, a Phase 3 study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 838 participants
- Enrollment target
Study Summary
This randomized controlled trial will evaluate whether intravenous thyroxine infusion given to brain-dead organ donors who are eligible to donate hearts for 12 hours will result in more hearts transplanted than saline placebo
Primary Outcome
Whether heart is transplanted into living recipient
Interventions
- DRUG Saline
- DRUG Thyroxine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 838 participants |
| Start Date | 2020-12-01 |
| Est. Completion | 2022-12-06 |
| Phase | Phase 3 |
What the finished NCT04415658 record still lists
NCT04415658 is an interventional study that assigns participants to a tested intervention. The registered 838 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which Saline is the first listed.
NCT04415658 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04415658 about?
NCT04415658 is a clinical study titled "Intravenous Thyroxine for Heart-Eligible Organ Donors". This randomized controlled trial will evaluate whether intravenous thyroxine infusion given to brain-dead organ donors who are eligible to donate hearts for 12 hours will result in more hearts transplanted than saline placebo
What is the current status of trial NCT04415658?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 838 participants. The study started on 2020-12-01. Estimated completion is 2022-12-06.
What interventions are being tested in trial NCT04415658?
The interventions under investigation include: Saline (DRUG), Thyroxine (DRUG).
Who is sponsoring clinical trial NCT04415658?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04415658's enrollment target sits among peer trials
838 394th of 2000 higher than 1,606 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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