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NCT04412824 · ClinicalTrials.gov registry record · Early Phase 1
Multimodal Neuroimaging of Alcohol Cues, Cortisol Response, and Compulsive Motivation
A Early Phase 1 study, sponsored by Auburn University.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 87
- Enrollment target
NCT04412824: Completed Early Phase 1 study, sponsored by Auburn University.
NCT04412824 is a Early Phase 1 study that has completed, run by Auburn University. The registered enrollment target is 87 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (64% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04412824, a Early Phase 1 study, has completed, sponsored by Auburn University.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 87 participants
- Enrollment target
Study Summary
This study proposes to examine both the peripheral and central nervous system responses when light social drinkers and binge/heavy social drinkers are exposed to visual ethanol cues, followed by oral ethanol. The findings will provide a greater understanding of the brain mechanisms (cerebral blood flow and functional connectivity) underlying the association between stress, cortisol release, alcohol craving, and alcohol stimulant and sedative effects. This knowledge could be significant in developing new therapies for the treatment of alcoholism.
Primary Outcome
Blood flow is measured in ml/100 grams/minute. The interpretation is that blood flow to that area indicates that region of the brain is responding to the visual alcohol or non-alcoholic beverage cues. Change in blood flow will be calculated as the change (and slope) of measurements taken at 10, 20, 30 and 45 minutes during the procedure.
Interventions
- DRUG Intravenous blood draw
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 87 participants |
| Start Date | 2020-05-22 |
| Est. Completion | 2021-12-31 |
| Phase | Early Phase 1 |
What the finished NCT04412824 record still lists
NCT04412824 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 87 participants, a relatively small participant target, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (64% higher).
The record links to 0 conditions, and to 1 intervention - of which Intravenous blood draw is the first listed.
NCT04412824 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04412824 about?
NCT04412824 is a clinical study titled "Multimodal Neuroimaging of Alcohol Cues, Cortisol Response, and Compulsive Motivation". This study proposes to examine both the peripheral and central nervous system responses when light social drinkers and binge/heavy social drinkers are exposed to visual ethanol cues, followed by oral ethanol. The findings will provide a greater understanding of the brain mechanisms (cerebral blood f...
What is the current status of trial NCT04412824?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 87 participants. The study started on 2020-05-22. Estimated completion is 2021-12-31.
What interventions are being tested in trial NCT04412824?
The interventions under investigation include: Intravenous blood draw (DRUG).
Who is sponsoring clinical trial NCT04412824?
This trial is sponsored by Auburn University, which has 54 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04412824's enrollment target sits among peer trials
87 251st of 2000 higher than 1,746 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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