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NCT04412616 · ClinicalTrials.gov registry record · Phase 1

ZZ06 in Adult Patients With Advanced Solid Tumor Malignancies

A Phase 1 study of Advanced EGFR Positive Solid Tumor, sponsored by Changchun Intellicrown Pharmaceutical Co..

Recruiting
Registry status
Phase 1
Development phase
60
Enrollment target
5
Study locations

NCT04412616 is a Phase 1 study of Advanced EGFR Positive Solid Tumor that is actively recruiting participants, run by Changchun Intellicrown Pharmaceutical Co.. The registered enrollment target is 60 participants. The trial reports 5 study locations across 4 states.

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The verdict

NCT04412616, a Phase 1 study of Advanced EGFR Positive Solid Tumor, is actively recruiting participants, sponsored by Changchun Intellicrown Pharmaceutical Co..

RECRUITING
Registry status
Phase 1
Development phase
60 participants
Enrollment target
5
Study locations

Study Summary

This is a Phase 1, Multicenter, Open-label study to assess the safety, tolerability and preliminary efficacy of ZZ06 in participants with all Adult Patients with Advanced EGFR-positive Solid Tumor Malignancies who are not able to have current standard anti-tumor therapies. The purpose of this study is to determine the maximum tolerated dose (MTD) , to characterise the safety, pharmacokinetics (PK), immunogenicity, pharmacodynamics (PD) and anti-tumor activity of ZZ06 as a single agent in adult participants with advanced solid tumors.

Interventions

  • BIOLOGICAL ZZ06

Study Locations (5)

Jilin

  • Jilin Cancer Hospital - Changchun
  • The first Bethune hospital of Jilin University - Changchun

California

  • Cedars Sinai Medical Center - Los Angeles

Kansas

  • Kansas University Cancer Center - Fairway

New York

  • Montefiore Medical Center - The Bronx

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2020-09-01
Est. Completion 2026-07-06
Phase Phase 1

What the Registry Record Tells You About NCT04412616

The ClinicalTrials.gov registry entry for NCT04412616 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Changchun Intellicrown Pharmaceutical Co., which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Advanced EGFR Positive Solid Tumor appearing as the primary indexed condition, and to 1 intervention - of which ZZ06 is the first listed.

NCT04412616 reports 5 study locations spanning 4 distinct geographic areas - top geographies include Jilin, California, Kansas.

Frequently Asked Questions

What is clinical trial NCT04412616 about?

NCT04412616 is a clinical study titled "ZZ06 in Adult Patients With Advanced Solid Tumor Malignancies". This is a Phase 1, Multicenter, Open-label study to assess the safety, tolerability and preliminary efficacy of ZZ06 in participants with all Adult Patients with Advanced EGFR-positive Solid Tumor Malignancies who are not able to have current standard anti-tumor therapies. The purpose of this study ...

What is the current status of trial NCT04412616?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2020-09-01. Estimated completion is 2026-07-06.

What conditions does trial NCT04412616 study?

This clinical trial studies the following conditions: Advanced EGFR Positive Solid Tumor.

What interventions are being tested in trial NCT04412616?

The interventions under investigation include: ZZ06 (BIOLOGICAL).

Who is sponsoring clinical trial NCT04412616?

This trial is sponsored by Changchun Intellicrown Pharmaceutical Co., which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04412616 being conducted?

This trial has 5 study locations across California, Kansas, New York, Jilin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.