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NCT04403139 · ClinicalTrials.gov registry record · Phase 4

VZV-specific Tissue Resident Memory T-cells After Shingrix Vaccination

A Phase 4 study of Varicella Zoster Virus Infection, sponsored by University of Washington.

Active
Registry status
Phase 4
Development phase
50
Enrollment target
1
Study location

NCT04403139: Active Phase 4 study of Varicella Zoster Virus Infection, sponsored by University of Washington.

NCT04403139 is a Phase 4 study of Varicella Zoster Virus Infection that is active but no longer recruiting, run by University of Washington. The registered enrollment target is 50 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04403139, a Phase 4 study of Varicella Zoster Virus Infection, is active but no longer recruiting, sponsored by University of Washington.

ACTIVE NOT RECRUITING
Registry status
Phase 4
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

To evaluate the effect of intramuscular RZV vaccine on VZV-specific skin TRM and circulating T-cells

Primary Outcome

Units will be optical density at 492 nanometers from ELISA.

Interventions

  • DRUG Shingrix

Study Locations (1)

Washington

  • University of Washington Virology Research Clinic - Seattle

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2022-04-27
Est. Completion 2026-02
Phase Phase 4
University of Washington

1,048 total trials

What the registry record for NCT04403139 still lists

NCT04403139 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower).

The record links to 1 condition, with Varicella Zoster Virus Infection appearing as the primary indexed condition, and to 1 intervention - of which Shingrix is the first listed.

NCT04403139 reports a single indexed study location in Washington.

Frequently Asked Questions

What is clinical trial NCT04403139 about?

NCT04403139 is a clinical study titled "VZV-specific Tissue Resident Memory T-cells After Shingrix Vaccination". To evaluate the effect of intramuscular RZV vaccine on VZV-specific skin TRM and circulating T-cells

What is the current status of trial NCT04403139?

This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 50 participants. The study started on 2022-04-27. Estimated completion is 2026-02.

What conditions does trial NCT04403139 study?

This clinical trial studies the following conditions: Varicella Zoster Virus Infection.

What interventions are being tested in trial NCT04403139?

The interventions under investigation include: Shingrix (DRUG).

Who is sponsoring clinical trial NCT04403139?

This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04403139 being conducted?

This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Varicella Zoster Virus Infection

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04403139's enrollment target sits among peer trials

50 1255th of 2000 higher than 679 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04403139, the US trial registry maintained by the National Library of Medicine. NCT04403139 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.