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NCT04401423 · ClinicalTrials.gov registry record · Phase 2

TXA127 for the Treatment of Severe COVID-19

A Phase 2 study, sponsored by Columbia University.

Completed
Registry status
Phase 2
Development phase
22
Enrollment target

NCT04401423 is a Phase 2 study that has completed, run by Columbia University. The registered enrollment target is 22 participants.

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The verdict

NCT04401423, a Phase 2 study, has completed, sponsored by Columbia University.

COMPLETED
Registry status
Phase 2
Development phase
22 participants
Enrollment target

Study Summary

The purpose of this study is to determine if administration of angiotensin-(1-7) (TXA127) prevents acute kidney injury and deterioration into multi-organ failure in patients with severe COVID-19. Participants will undergo a 10-day treatment with either placebo or study drug. The drug will be administered intravenously for 3 hours once each day for 10 days consecutively.

Interventions

  • DRUG Placebo
  • DRUG TXA127

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2021-02-10
Est. Completion 2021-06-10
Phase Phase 2

Sponsor

Columbia University

958 total trials

What the Registry Record Tells You About NCT04401423

The ClinicalTrials.gov registry entry for NCT04401423 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04401423 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04401423 about?

NCT04401423 is a clinical study titled "TXA127 for the Treatment of Severe COVID-19". The purpose of this study is to determine if administration of angiotensin-(1-7) (TXA127) prevents acute kidney injury and deterioration into multi-organ failure in patients with severe COVID-19. Participants will undergo a 10-day treatment with either placebo or study drug. The drug will be adminis...

What is the current status of trial NCT04401423?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 22 participants. The study started on 2021-02-10. Estimated completion is 2021-06-10.

What interventions are being tested in trial NCT04401423?

The interventions under investigation include: Placebo (DRUG), TXA127 (DRUG).

Who is sponsoring clinical trial NCT04401423?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.