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NCT04396847 · ClinicalTrials.gov registry record · Phase 2
Laboratory Screening of Lorcaserin for Alcohol Use Disorder
A Phase 2 study, sponsored by The Mind Research Network.
- Terminated
- Registry status
- Phase 2
- Development phase
- 5
- Enrollment target
NCT04396847: Clinical Trial Phase 2 study, sponsored by The Mind Research Network.
NCT04396847 is a Phase 2 study that was terminated before completion, run by The Mind Research Network. The registered enrollment target is 5 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04396847, a Phase 2 study, was terminated before completion, sponsored by The Mind Research Network.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 5 participants
- Enrollment target
Study Summary
Heavy-drinking smokers, including those with alcohol use disorder (AUD), are at increased risk for numerous negative health outcomes relative to those who use alcohol or cigarettes only. Although heavy-drinking smokers are recognized as an important subgroup for clinical and public health interventions, there are presently no approved medications for the joint indication of alcohol reduction and smoking cessation. Based on evidence that the serotonin system plays a role in alcohol and nicotine consumption and relapse, this study aims to examine whether a serotonin medication alters alcohol and nicotine responses in smokers with AUD, informing its potential utility as a candidate therapy for this clinical subgroup.
Primary Outcome
Number of drinks consumed during a 2-hour alcohol self-administration session
Interventions
- DRUG Placebo oral tablet
- DRUG Lorcaserin Oral Tablet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2019-10-25 |
| Est. Completion | 2020-02-26 |
| Phase | Phase 2 |
Why NCT04396847 stopped before completion
NCT04396847 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo oral tablet is the first listed.
NCT04396847 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04396847 about?
NCT04396847 is a clinical study titled "Laboratory Screening of Lorcaserin for Alcohol Use Disorder". Heavy-drinking smokers, including those with alcohol use disorder (AUD), are at increased risk for numerous negative health outcomes relative to those who use alcohol or cigarettes only. Although heavy-drinking smokers are recognized as an important subgroup for clinical and public health interventi...
What is the current status of trial NCT04396847?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 5 participants. The study started on 2019-10-25. Estimated completion is 2020-02-26.
What interventions are being tested in trial NCT04396847?
The interventions under investigation include: Placebo oral tablet (DRUG), Lorcaserin Oral Tablet (DRUG).
Who is sponsoring clinical trial NCT04396847?
This trial is sponsored by The Mind Research Network, which has 17 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04396847's enrollment target sits among peer trials
5 2000th of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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