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NCT04396834 · ClinicalTrials.gov registry record · Phase 2
Mechanisms of Lorcaserin for Smoking Cessation
A Phase 2 study, sponsored by The Mind Research Network.
- Terminated
- Registry status
- Phase 2
- Development phase
- 3
- Enrollment target
NCT04396834: Clinical Trial Phase 2 study, sponsored by The Mind Research Network.
NCT04396834 is a Phase 2 study that was terminated before completion, run by The Mind Research Network. The registered enrollment target is 3 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04396834, a Phase 2 study, was terminated before completion, sponsored by The Mind Research Network.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 3 participants
- Enrollment target
Study Summary
Identifying new medication options is critical for curbing the health burdens of cigarette smoking. Currently approved smoking cessation medications act on nicotinic receptors, and additional work is needed to identify medications with alternate pharmacological targets. Based on evidence that the serotonin system plays a role in nicotine consumption and relapse, this study will examine whether a selective serotonin medication alters smoking-related behaviors and responses to cigarette smoking under controlled conditions, informing its potential utility for smoking cessation.
Primary Outcome
Duration (in minutes) until lapsing to smoking during a 50-minute period
Interventions
- DRUG Placebo oral tablet
- DRUG Lorcaserin Oral Tablet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2019-12-04 |
| Est. Completion | 2020-02-26 |
| Phase | Phase 2 |
Why NCT04396834 stopped before completion
NCT04396834 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo oral tablet is the first listed.
NCT04396834 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04396834 about?
NCT04396834 is a clinical study titled "Mechanisms of Lorcaserin for Smoking Cessation". Identifying new medication options is critical for curbing the health burdens of cigarette smoking. Currently approved smoking cessation medications act on nicotinic receptors, and additional work is needed to identify medications with alternate pharmacological targets. Based on evidence that the se...
What is the current status of trial NCT04396834?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 3 participants. The study started on 2019-12-04. Estimated completion is 2020-02-26.
What interventions are being tested in trial NCT04396834?
The interventions under investigation include: Placebo oral tablet (DRUG), Lorcaserin Oral Tablet (DRUG).
Who is sponsoring clinical trial NCT04396834?
This trial is sponsored by The Mind Research Network, which has 17 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04396834's enrollment target sits among peer trials
3 2001st of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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