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NCT04395183 · ClinicalTrials.gov registry record · Phase 2
5-HTP and Creatine for Depression
A Phase 2 study, sponsored by University of Utah.
- Completed
- Registry status
- Phase 2
- Development phase
- 43
- Enrollment target
NCT04395183 is a Phase 2 study that has completed, run by University of Utah. The registered enrollment target is 43 participants.
The verdict
NCT04395183, a Phase 2 study, has completed, sponsored by University of Utah.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 43 participants
- Enrollment target
Study Summary
This is a three-armed clinical trial examining the effect of 5-hydroxytryptophan and creatine monohydrate as augmenting agents for the treatment of depression. Subjects will be randomized between 5-HTP + placebo, creatine + placebo, and 5-HTP + creatine, for 8 weeks. The ability of the interventions to affect biomarkers associated with depression will be assessed using brain phosphorus magnetic resonance spectroscopy, functional connectivity imaging, and plasma serotonin levels.
Interventions
- DRUG Placebo
- DRUG Creatine monohydrate
- DRUG 5-Hydroxytryptophan 100 MG
- DRUG placebo matched to 5-HTP
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 43 participants |
| Start Date | 2021-03-01 |
| Est. Completion | 2024-03-01 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04395183
The ClinicalTrials.gov registry entry for NCT04395183 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 43 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Utah, which has 818 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.
NCT04395183 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04395183 about?
NCT04395183 is a clinical study titled "5-HTP and Creatine for Depression". This is a three-armed clinical trial examining the effect of 5-hydroxytryptophan and creatine monohydrate as augmenting agents for the treatment of depression. Subjects will be randomized between 5-HTP + placebo, creatine + placebo, and 5-HTP + creatine, for 8 weeks. The ability of the interventions...
What is the current status of trial NCT04395183?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 43 participants. The study started on 2021-03-01. Estimated completion is 2024-03-01.
What interventions are being tested in trial NCT04395183?
The interventions under investigation include: Placebo (DRUG), Creatine monohydrate (DRUG), 5-Hydroxytryptophan 100 MG (DRUG), placebo matched to 5-HTP (DRUG).
Who is sponsoring clinical trial NCT04395183?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
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