Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04390243 · ClinicalTrials.gov registry record · Phase 2

Binimetinib and Encorafenib for the Treatment of Pancreatic Cancer in Patients With a Somatic BRAF V600E Mutation

A Phase 2 study, sponsored by Academic and Community Cancer Research United.

Terminated
Registry status
Phase 2
Development phase
6
Enrollment target

NCT04390243 is a Phase 2 study that was terminated before completion, run by Academic and Community Cancer Research United. The registered enrollment target is 6 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04390243, a Phase 2 study, was terminated before completion, sponsored by Academic and Community Cancer Research United.

TERMINATED
Registry status
Phase 2
Development phase
6 participants
Enrollment target

Study Summary

This phase II trial studies the side effects and how well the combination of binimetinib and encorafenib work in treating patients with pancreatic cancer with a somatic BRAF V600E mutation. Binimetinib and encorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving binimetinib and encorafenib may work better compared to the usual treatment in treating patients with pancreatic cancer and a somatic BRAF V600E mutation.

Interventions

  • DRUG Binimetinib
  • DRUG Encorafenib

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2020-11-16
Est. Completion 2023-11-01
Phase Phase 2

What the Registry Record Tells You About NCT04390243

The ClinicalTrials.gov registry entry for NCT04390243 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 6 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Academic and Community Cancer Research United, which has 42 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Binimetinib is the first listed.

NCT04390243 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04390243 about?

NCT04390243 is a clinical study titled "Binimetinib and Encorafenib for the Treatment of Pancreatic Cancer in Patients With a Somatic BRAF V600E Mutation". This phase II trial studies the side effects and how well the combination of binimetinib and encorafenib work in treating patients with pancreatic cancer with a somatic BRAF V600E mutation. Binimetinib and encorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell...

What is the current status of trial NCT04390243?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 6 participants. The study started on 2020-11-16. Estimated completion is 2023-11-01.

What interventions are being tested in trial NCT04390243?

The interventions under investigation include: Binimetinib (DRUG), Encorafenib (DRUG).

Who is sponsoring clinical trial NCT04390243?

This trial is sponsored by Academic and Community Cancer Research United, which has 42 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.