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NCT04389450 · ClinicalTrials.gov registry record · Phase 2
Double-Blind, Multicenter, Study to Evaluate the Efficacy of PLX PAD for the Treatment of COVID-19
A Phase 2 study, sponsored by Pluristem.
- Terminated
- Registry status
- Phase 2
- Development phase
- 66
- Enrollment target
NCT04389450: Clinical Trial Phase 2 study, sponsored by Pluristem.
NCT04389450 is a Phase 2 study that was terminated before completion, run by Pluristem. The registered enrollment target is 66 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04389450, a Phase 2 study, was terminated before completion, sponsored by Pluristem.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 66 participants
- Enrollment target
Study Summary
This clinical trial will examine if a new treatment of Mesenchymal-like Adherent stromal Cells (called PLX-PAD) can help patients intubated and mechanically ventilated due to COVID-19 to recover more quickly with less complications.
Interventions
- BIOLOGICAL Placebo
- BIOLOGICAL PLX-PAD
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 66 participants |
| Start Date | 2020-10-01 |
| Est. Completion | 2023-06-07 |
| Phase | Phase 2 |
Why NCT04389450 stopped before completion
NCT04389450 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04389450 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04389450 about?
NCT04389450 is a clinical study titled "Double-Blind, Multicenter, Study to Evaluate the Efficacy of PLX PAD for the Treatment of COVID-19". This clinical trial will examine if a new treatment of Mesenchymal-like Adherent stromal Cells (called PLX-PAD) can help patients intubated and mechanically ventilated due to COVID-19 to recover more quickly with less complications.
What is the current status of trial NCT04389450?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 66 participants. The study started on 2020-10-01. Estimated completion is 2023-06-07.
What interventions are being tested in trial NCT04389450?
The interventions under investigation include: Placebo (BIOLOGICAL), PLX-PAD (BIOLOGICAL).
Who is sponsoring clinical trial NCT04389450?
This trial is sponsored by Pluristem, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04389450's enrollment target sits among peer trials
66 975th of 2000 higher than 1,014 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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