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NCT04383314 · ClinicalTrials.gov registry record · NA
Targeting Hyaluronan Accumulation Through Exercise in T2DM
A NA study, sponsored by NYU Langone Health.
- Completed
- Registry status
- NA
- Development phase
- 30
- Enrollment target
NCT04383314: Completed NA study, sponsored by NYU Langone Health.
NCT04383314 is a NA study that has completed, run by NYU Langone Health. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04383314, a NA study, has completed, sponsored by NYU Langone Health.
- COMPLETED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
Study Summary
A pilot longitudinal study to examine hyaluronan (HA) accumulation in muscles of individuals with Type 2 diabetes mellitus (T2DM), and the effects of exercise on HA accumulation, muscle stiffness, strength, ankle joint mobility, and physical function. HA accumulation will be assessed non- invasively using magnetic resonance imaging.
Primary Outcome
Hyaluronan accumulation (HA) in calf muscle will be assessed using 3D T1ρ and T2-weighted MR scans on a 3T whole-body clinical MRI scanner (Prisma, Siemens Healthcare, Erlangen, Germany) with a 15-channel knee coil (QED, Cleveland OH). The total scan time is expected to be 29 min, 30 s. The sequence acquisition parameters will be as follows: TR/TE = 1500 ms/3.78 ms, flip angle = 8°, field of view (FOV) = 140 mm2, spin-lock lengths (TSLs)=0,10ms, 20ms, 30ms, 40ms and 60ms, spin-lock frequency=500
Interventions
- BEHAVIORAL 10-week exercise program on HA accumulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2021-09-01 |
| Est. Completion | 2024-08-31 |
| Phase | NA |
What the finished NCT04383314 record still lists
NCT04383314 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which 10-week exercise program on HA accumulation is the first listed.
NCT04383314 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04383314 about?
NCT04383314 is a clinical study titled "Targeting Hyaluronan Accumulation Through Exercise in T2DM". A pilot longitudinal study to examine hyaluronan (HA) accumulation in muscles of individuals with Type 2 diabetes mellitus (T2DM), and the effects of exercise on HA accumulation, muscle stiffness, strength, ankle joint mobility, and physical function. HA accumulation will be assessed non- invasively...
What is the current status of trial NCT04383314?
This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2021-09-01. Estimated completion is 2024-08-31.
What interventions are being tested in trial NCT04383314?
The interventions under investigation include: 10-week exercise program on HA accumulation (BEHAVIORAL).
Who is sponsoring clinical trial NCT04383314?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04383314's enrollment target sits among peer trials
30 1593rd of 2000 higher than 299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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