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NCT04380805 · ClinicalTrials.gov registry record · Phase 2
A Study of AK104, a PD-1/CTLA-4 Bispecific Antibody in Subjects With Recurrent/Metastatic Cervical Cancer
A Phase 2 study, sponsored by Akeso.
- Completed
- Registry status
- Phase 2
- Development phase
- 30
- Enrollment target
NCT04380805: Completed Phase 2 study, sponsored by Akeso.
NCT04380805 is a Phase 2 study that has completed, run by Akeso. The registered enrollment target is 30 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04380805, a Phase 2 study, has completed, sponsored by Akeso.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 30 participants
- Enrollment target
Study Summary
This is a Phase 2, global, multicenter, open label, single arm study designed to evaluate the efficacy, safety, tolerability, pharmacokinetic (PK), and immunogenicity of AK104 monotherapy in adult subjects with previously treated recurrent or metastatic cervical carcinoma.
Interventions
- BIOLOGICAL AK104
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2020-07-15 |
| Est. Completion | 2023-01-31 |
| Phase | Phase 2 |
What the finished NCT04380805 record still lists
NCT04380805 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower).
The record links to 0 conditions, and to 1 intervention - of which AK104 is the first listed.
NCT04380805 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04380805 about?
NCT04380805 is a clinical study titled "A Study of AK104, a PD-1/CTLA-4 Bispecific Antibody in Subjects With Recurrent/Metastatic Cervical Cancer". This is a Phase 2, global, multicenter, open label, single arm study designed to evaluate the efficacy, safety, tolerability, pharmacokinetic (PK), and immunogenicity of AK104 monotherapy in adult subjects with previously treated recurrent or metastatic cervical carcinoma.
What is the current status of trial NCT04380805?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2020-07-15. Estimated completion is 2023-01-31.
What interventions are being tested in trial NCT04380805?
The interventions under investigation include: AK104 (BIOLOGICAL).
Who is sponsoring clinical trial NCT04380805?
This trial is sponsored by Akeso, which has 4 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04380805's enrollment target sits among peer trials
30 1582nd of 2000 higher than 332 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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