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NCT04372927 · ClinicalTrials.gov registry record · Phase 2

ADMIRAL Trial: Adaptive Mediastinal Radiation With Chemo-Immunotherapy

A Phase 2 study, sponsored by University of Washington.

Terminated
Registry status
Phase 2
Development phase
1
Enrollment target

NCT04372927 is a Phase 2 study that was terminated before completion, run by University of Washington. The registered enrollment target is 1 participants.

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The verdict

NCT04372927, a Phase 2 study, was terminated before completion, sponsored by University of Washington.

TERMINATED
Registry status
Phase 2
Development phase
1 participants
Enrollment target

Study Summary

This phase II trial studies two questions in patients with stage III NSCLC: 1) does it improve cancer control to add the drug Durvalumab, a type of immunotherapy, earlier in the treatment course; and 2) by intensifying treatment with durvalumab, is it possible to avoid mediastinal radiation to decrease side effects, without decreasing cancer control?

Interventions

  • DRUG Cisplatin
  • DRUG Pemetrexed
  • BIOLOGICAL Durvalumab
  • DRUG Etoposide
  • RADIATION Hypofractionated Radiation Therapy

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2021-12-10
Est. Completion 2022-04-23
Phase Phase 2

Sponsor

University of Washington

1,048 total trials

What the Registry Record Tells You About NCT04372927

The ClinicalTrials.gov registry entry for NCT04372927 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 1 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Washington, which has 1,048 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Cisplatin is the first listed.

NCT04372927 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04372927 about?

NCT04372927 is a clinical study titled "ADMIRAL Trial: Adaptive Mediastinal Radiation With Chemo-Immunotherapy". This phase II trial studies two questions in patients with stage III NSCLC: 1) does it improve cancer control to add the drug Durvalumab, a type of immunotherapy, earlier in the treatment course; and 2) by intensifying treatment with durvalumab, is it possible to avoid mediastinal radiation to decre...

What is the current status of trial NCT04372927?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 1 participants. The study started on 2021-12-10. Estimated completion is 2022-04-23.

What interventions are being tested in trial NCT04372927?

The interventions under investigation include: Cisplatin (DRUG), Pemetrexed (DRUG), Durvalumab (BIOLOGICAL), Etoposide (DRUG), Hypofractionated Radiation Therapy (RADIATION).

Who is sponsoring clinical trial NCT04372927?

This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.