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NCT04372914 · ClinicalTrials.gov registry record · NA
Prevention of Oral DNA Damage by Black Raspberries
A NA study, sponsored by Milton S. Hershey Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 69
- Enrollment target
NCT04372914: Completed NA study, sponsored by Milton S. Hershey Medical Center.
NCT04372914 is a NA study that has completed, run by Milton S. Hershey Medical Center. The registered enrollment target is 69 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04372914, a NA study, has completed, sponsored by Milton S. Hershey Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 69 participants
- Enrollment target
Study Summary
The purpose of this voluntary research study is to learn about the potential effects that black raspberry (BRB) lozenges may have on reducing the damage caused from cigarette smoke in mouth cells in adult smokers, which may be useful in reducing health risks associated with smoking.
Primary Outcome
The tobacco specific nitrosamine, N'-nitrosonornicotine, is metabolically activated to form DNA adduct that upon hydrolysis releases 4-hydroxy-1-(3-pyridyl)-1-butonone (HPB), which was measured in buccal cells of smokers in picogram per microgram guanine (one of the four bases of DNA).
Interventions
- DIETARY_SUPPLEMENT BRB Lozenges
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 69 participants |
| Start Date | 2021-10-07 |
| Est. Completion | 2024-12-06 |
| Phase | NA |
What the finished NCT04372914 record still lists
NCT04372914 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 69 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 1 intervention - of which BRB Lozenges is the first listed.
NCT04372914 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04372914 about?
NCT04372914 is a clinical study titled "Prevention of Oral DNA Damage by Black Raspberries". The purpose of this voluntary research study is to learn about the potential effects that black raspberry (BRB) lozenges may have on reducing the damage caused from cigarette smoke in mouth cells in adult smokers, which may be useful in reducing health risks associated with smoking.
What is the current status of trial NCT04372914?
This trial is currently completed. It is a NA study. The enrollment target is 69 participants. The study started on 2021-10-07. Estimated completion is 2024-12-06.
What interventions are being tested in trial NCT04372914?
The interventions under investigation include: BRB Lozenges (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT04372914?
This trial is sponsored by Milton S. Hershey Medical Center, which has 396 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04372914's enrollment target sits among peer trials
69 1133rd of 2000 higher than 868 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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