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NCT04372186 · ClinicalTrials.gov registry record · Phase 3

A Study to Evaluate the Efficacy and Safety of Tocilizumab in Hospitalized Participants With COVID-19 Pneumonia

A Phase 3 study, sponsored by Genentech.

Completed
Registry status
Phase 3
Development phase
377
Enrollment target

NCT04372186 is a Phase 3 study that has completed, run by Genentech. The registered enrollment target is 377 participants.

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The verdict

NCT04372186, a Phase 3 study, has completed, sponsored by Genentech.

COMPLETED
Registry status
Phase 3
Development phase
377 participants
Enrollment target

Study Summary

This study (EMPACTA) will a) evaluate the efficacy and safety of tocilizumab (TCZ) compared with a placebo in combination with standard of care (SOC) in hospitalized participants with COVID-19 pneumonia, and b) include an optional long-term extension for eligible participants to explore the long-term sequelae of resolved COVID-19 pneumonia.

Interventions

  • DRUG Placebo
  • DRUG Tocilizumab

Trial Details

FieldValue
Enrollment Target 377 participants
Start Date 2020-05-14
Est. Completion 2020-09-22
Phase Phase 3

Sponsor

Genentech

332 total trials

What the Registry Record Tells You About NCT04372186

The ClinicalTrials.gov registry entry for NCT04372186 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 377 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Genentech, which has 332 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04372186 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04372186 about?

NCT04372186 is a clinical study titled "A Study to Evaluate the Efficacy and Safety of Tocilizumab in Hospitalized Participants With COVID-19 Pneumonia". This study (EMPACTA) will a) evaluate the efficacy and safety of tocilizumab (TCZ) compared with a placebo in combination with standard of care (SOC) in hospitalized participants with COVID-19 pneumonia, and b) include an optional long-term extension for eligible participants to explore the long-ter...

What is the current status of trial NCT04372186?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 377 participants. The study started on 2020-05-14. Estimated completion is 2020-09-22.

What interventions are being tested in trial NCT04372186?

The interventions under investigation include: Placebo (DRUG), Tocilizumab (DRUG).

Who is sponsoring clinical trial NCT04372186?

This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.