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NCT04366544 · ClinicalTrials.gov registry record · NA
Effects of an 8-day Advanced Meditation, Samyama on Physical, Psychological and Spiritual Wellbeing ,and Associated Neural Mechanisms
A NA study, sponsored by Indiana University.
- Completed
- Registry status
- NA
- Development phase
- 759
- Enrollment target
NCT04366544: Completed NA study, sponsored by Indiana University.
NCT04366544 is a NA study that has completed, run by Indiana University. The registered enrollment target is 759 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (46% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04366544, a NA study, has completed, sponsored by Indiana University.
- COMPLETED
- Registry status
- NA
- Development phase
- 759 participants
- Enrollment target
Study Summary
The purpose of this study is to investigate the effects of Samyama program on blood levels of selected neurotransmitters before and after the program, and associate with corresponding effects on mind/psyche before and after the program in adult participants. Hypothesis: 1. The state of higher consciousness and ecstasy resulting from Samyama result from increased levels of Anandamide, an endocannabinoid, and Brain Derived Neurotrophic Factor (BDNF). 2. The 60-day preparatory phase that includes dietary regulation and yogic practices will reduce the gut inflammation and thereby will improve the gut microbiome.
Primary Outcome
Anandamide (AEA) activates endocannabinoid-1 (eCB1) receptors in the central nervous system and eCB2 receptors throughout the body and studies have suggested its role in regulating mood and behavior, sleeping and eating patterns, memory, pain, immune system, fertility and cancer inhibition \[3\]. Endogenous anandamide is mainly active at eCB1 receptor, which is responsible for the experience of blissfulness, ecstasy and the elevated mood and wellbeing similar to psychoactive effects reported in
Interventions
- OTHER Part A1: Survey
- OTHER Part A2: Sample collection
- OTHER Part B:
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 759 participants |
| Start Date | 2018-01-19 |
| Est. Completion | 2018-07-31 |
| Phase | NA |
What the finished NCT04366544 record still lists
NCT04366544 is an interventional study that assigns participants to a tested intervention. The registered 759 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (46% lower).
The record links to 0 conditions, and to 3 interventions - of which Part A1: Survey is the first listed.
NCT04366544 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04366544 about?
NCT04366544 is a clinical study titled "Effects of an 8-day Advanced Meditation, Samyama on Physical, Psychological and Spiritual Wellbeing ,and Associated Neural Mechanisms". The purpose of this study is to investigate the effects of Samyama program on blood levels of selected neurotransmitters before and after the program, and associate with corresponding effects on mind/psyche before and after the program in adult participants. Hypothesis: 1. The state of higher cons...
What is the current status of trial NCT04366544?
This trial is currently completed. It is a NA study. The enrollment target is 759 participants. The study started on 2018-01-19. Estimated completion is 2018-07-31.
What interventions are being tested in trial NCT04366544?
The interventions under investigation include: Part A1: Survey (OTHER), Part A2: Sample collection (OTHER), Part B: (OTHER).
Who is sponsoring clinical trial NCT04366544?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04366544's enrollment target sits among peer trials
759 145th of 2000 higher than 1,856 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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