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NCT04362189 · ClinicalTrials.gov registry record · Phase 2
Efficacy and Safety Study of Allogeneic HB-adMSCs for the Treatment of COVID-19
A Phase 2 study, sponsored by Hope Biosciences Research Foundation.
- Terminated
- Registry status
- Phase 2
- Development phase
- 48
- Enrollment target
NCT04362189: Clinical Trial Phase 2 study, sponsored by Hope Biosciences Research Foundation.
NCT04362189 is a Phase 2 study that was terminated before completion, run by Hope Biosciences Research Foundation. The registered enrollment target is 48 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (64% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04362189, a Phase 2 study, was terminated before completion, sponsored by Hope Biosciences Research Foundation.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 48 participants
- Enrollment target
Study Summary
Hope Biosciences is conducting a research study of an investigational product called allogeneic adipose-derived mesenchymal stem cells (abbreviated as HB-adMSCs) as treatment for patients suspected to have COVID-19. The study purpose is to evaluate the safety and efficacy of four IV infusions of either placebo or HB-adMSCs in subjects with COVID-19.
Primary Outcome
Change from baseline in Tumor Necrosis Factor-Alpha (TNF-alpha) in the blood (pg/mL)
Interventions
- OTHER Placebo
- BIOLOGICAL HB-adMSC
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2020-06-30 |
| Est. Completion | 2021-09-30 |
| Phase | Phase 2 |
Why NCT04362189 stopped before completion
NCT04362189 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (64% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04362189 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04362189 about?
NCT04362189 is a clinical study titled "Efficacy and Safety Study of Allogeneic HB-adMSCs for the Treatment of COVID-19". Hope Biosciences is conducting a research study of an investigational product called allogeneic adipose-derived mesenchymal stem cells (abbreviated as HB-adMSCs) as treatment for patients suspected to have COVID-19. The study purpose is to evaluate the safety and efficacy of four IV infusions of eit...
What is the current status of trial NCT04362189?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 48 participants. The study started on 2020-06-30. Estimated completion is 2021-09-30.
What interventions are being tested in trial NCT04362189?
The interventions under investigation include: Placebo (OTHER), HB-adMSC (BIOLOGICAL).
Who is sponsoring clinical trial NCT04362189?
This trial is sponsored by Hope Biosciences Research Foundation, which has 9 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04362189's enrollment target sits among peer trials
48 1265th of 2000 higher than 718 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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