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NCT04360174 · ClinicalTrials.gov registry record · Phase 1
CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular Hypertension
A Phase 1 study, sponsored by Ocular Therapeutix.
- Completed
- Registry status
- Phase 1
- Development phase
- 19
- Enrollment target
NCT04360174: Completed Phase 1 study, sponsored by Ocular Therapeutix.
NCT04360174 is a Phase 1 study that has completed, run by Ocular Therapeutix. The registered enrollment target is 19 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04360174, a Phase 1 study, has completed, sponsored by Ocular Therapeutix.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 19 participants
- Enrollment target
Study Summary
To assess the safety, tolerability and efficacy of a single sustained release dose of OTX-TIC, a sustained release travoprost drug product, in subjects with primary open-angle glaucoma or ocular hypertension.
Primary Outcome
All adverse events will be captured throughout the study
Interventions
- DRUG OTX-TIC
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2018-04-25 |
| Est. Completion | 2021-05-24 |
| Phase | Phase 1 |
What the finished NCT04360174 record still lists
NCT04360174 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (68% lower).
The record links to 0 conditions, and to 1 intervention - of which OTX-TIC is the first listed.
NCT04360174 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04360174 about?
NCT04360174 is a clinical study titled "CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular Hypertension". To assess the safety, tolerability and efficacy of a single sustained release dose of OTX-TIC, a sustained release travoprost drug product, in subjects with primary open-angle glaucoma or ocular hypertension.
What is the current status of trial NCT04360174?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2018-04-25. Estimated completion is 2021-05-24.
What interventions are being tested in trial NCT04360174?
The interventions under investigation include: OTX-TIC (DRUG).
Who is sponsoring clinical trial NCT04360174?
This trial is sponsored by Ocular Therapeutix, which has 20 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04360174's enrollment target sits among peer trials
19 1716th of 2000 higher than 281 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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