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NCT04353271 · ClinicalTrials.gov registry record · Phase 2
Trial of Hydroxychloroquine In Covid-19 Kinetics
A Phase 2 study, sponsored by University of South Alabama.
- Terminated
- Registry status
- Phase 2
- Development phase
- 3
- Enrollment target
NCT04353271: Clinical Trial Phase 2 study, sponsored by University of South Alabama.
NCT04353271 is a Phase 2 study that was terminated before completion, run by University of South Alabama. The registered enrollment target is 3 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04353271, a Phase 2 study, was terminated before completion, sponsored by University of South Alabama.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 3 participants
- Enrollment target
Study Summary
To test if the medication Hydroxychloroquine will decrease the amount of virus(as measured by PCR) , 7 days after initiation of therapy compared to control patients receiving placebo. The study design is a randomized (5 days of medication v. 5 days of placebo) clinical trial initiated immediately after diagnosis in ambulatory health care workers at University of South Alabama Health, or in ambulatory USA patients. At 7 days after enrollment another nasopharyngeal swab will be taken to measure if the virus is still present. At 10 weeks we will measure immunity from Covid-19 using a single blood sample. It is a phase 2/3 clinical trial.
Primary Outcome
Nasopharyngeal swab PCR measurement of viral load expressed as the % of negative PCR swabs
Interventions
- OTHER Placebo
- DRUG Hydroxychloroquine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2020-04-17 |
| Est. Completion | 2020-07-08 |
| Phase | Phase 2 |
Why NCT04353271 stopped before completion
NCT04353271 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04353271 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04353271 about?
NCT04353271 is a clinical study titled "Trial of Hydroxychloroquine In Covid-19 Kinetics". To test if the medication Hydroxychloroquine will decrease the amount of virus(as measured by PCR) , 7 days after initiation of therapy compared to control patients receiving placebo. The study design is a randomized (5 days of medication v. 5 days of placebo) clinical trial initiated immediately a...
What is the current status of trial NCT04353271?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 3 participants. The study started on 2020-04-17. Estimated completion is 2020-07-08.
What interventions are being tested in trial NCT04353271?
The interventions under investigation include: Placebo (OTHER), Hydroxychloroquine (DRUG).
Who is sponsoring clinical trial NCT04353271?
This trial is sponsored by University of South Alabama, which has 17 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04353271's enrollment target sits among peer trials
3 2001st of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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