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Craniofacial Microsomia: Accelerating Understanding of the Significance and Etiology

NCT04351893 · View on ClinicalTrials.gov ↗

Study Summary

The CAUSE study is a multicenter study, with domestic (n=4) and international (n=6) study sites. Children and young adults (ages 0-18) who have microtia and/or craniofacial microsomia and their parents are invited to participate. Children and parents are asked to provide a DNA sample (blood or saliva) and are asked to upload a few photos of their face. Parents are asked a short interview. Participants are able to participate from home or at one of four domestic sites.

Study Locations (10)

Other

  • Pontificia Universidad Javeriana — Bogotá
  • ICESI — Cali
  • Pontificia Universidad Javeriana — Cali
  • Clínica Comfamiliar Risaralda — Pereira
  • Hospital Edgardo Rebagliati Martins — Lima
  • Instituto de Genética Médica y Molecular (INGEMM) — Madrid

California

  • Children's Hospital Los Angeles — Los Angeles

North Carolina

  • University of North Carolina — Chapel Hill

Pennsylvania

  • Children's Hospital of Philadelphia — Philadelphia

Washington

  • Seattle Children's Hospital — Seattle

Trial Details

FieldValue
Enrollment Target 935 participants
Start Date 2018-02-23
Est. Completion 2023-08-30

Sponsor

Seattle Children's Hospital

127 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04351893

The ClinicalTrials.gov registry entry for NCT04351893 describes a study currently listed as completed. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 935 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Seattle Children's Hospital, which has 127 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 7 conditions, with Microtia appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04351893 reports 10 study locations spanning 5 distinct geographic areas — top geographies include Other, California, North Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04351893 about?

NCT04351893 is a clinical study titled "Craniofacial Microsomia: Accelerating Understanding of the Significance and Etiology". The CAUSE study is a multicenter study, with domestic (n=4) and international (n=6) study sites. Children and young adults (ages 0-18) who have microtia and/or craniofacial microsomia and their parents are invited to participate. Children and parents are asked to provide a DNA sample (blood or saliv...

What is the current status of trial NCT04351893?

This trial is currently completed. The enrollment target is 935 participants. The study started on 2018-02-23. Estimated completion is 2023-08-30.

What conditions does trial NCT04351893 study?

This clinical trial studies the following conditions: Microtia, Microtia-Anotia, Craniofacial Microsomia, Hemifacial Microsomia, Goldenhar Syndrome. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

Who is sponsoring clinical trial NCT04351893?

This trial is sponsored by Seattle Children's Hospital, which has 127 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04351893 being conducted?

This trial has 10 study locations across California, North Carolina, Pennsylvania, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial