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NCT04349072 · ClinicalTrials.gov registry record · Phase 3

A Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy

A Phase 3 study, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 3
Development phase
112
Enrollment target

NCT04349072 is a Phase 3 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 112 participants.

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The verdict

NCT04349072, a Phase 3 study, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 3
Development phase
112 participants
Enrollment target

Study Summary

This is a randomized, double-blind, placebo-controlled, multi-center study in the United States (U.S.) that will evaluate the effect of mavacamten treatment on reducing the number of septal reduction therapy (SRT) procedures performed in subjects with symptomatic obstructive hypertrophic cardiomyopathy (oHCM \[also known as HOCM\]) who are eligible for SRT based on ACCF/AHA 2011 and/or ESC 2014 guidelines.

Interventions

  • DRUG Placebo
  • DRUG Mavacamten

Trial Details

FieldValue
Enrollment Target 112 participants
Start Date 2020-07-06
Est. Completion 2024-05-20
Phase Phase 3

Sponsor

Bristol-Myers Squibb

1,025 total trials

What the Registry Record Tells You About NCT04349072

The ClinicalTrials.gov registry entry for NCT04349072 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 112 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bristol-Myers Squibb, which has 1,025 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04349072 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04349072 about?

NCT04349072 is a clinical study titled "A Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy". This is a randomized, double-blind, placebo-controlled, multi-center study in the United States (U.S.) that will evaluate the effect of mavacamten treatment on reducing the number of septal reduction therapy (SRT) procedures performed in subjects with symptomatic obstructive hypertrophic cardiomyopa...

What is the current status of trial NCT04349072?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 112 participants. The study started on 2020-07-06. Estimated completion is 2024-05-20.

What interventions are being tested in trial NCT04349072?

The interventions under investigation include: Placebo (DRUG), Mavacamten (DRUG).

Who is sponsoring clinical trial NCT04349072?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.