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NCT04342169 · ClinicalTrials.gov registry record · Phase 2
University of Utah COVID-19 Hydrochloroquine Trial
A Phase 2 study of Corona Virus Infection and Coronavirus, sponsored by University of Utah.
- Completed
- Registry status
- Phase 2
- Development phase
- 368
- Enrollment target
- 1
- Study location
NCT04342169: Completed Phase 2 study of Corona Virus Infection and Coronavirus, sponsored by University of Utah.
NCT04342169 is a Phase 2 study of Corona Virus Infection and Coronavirus that has completed, run by University of Utah. The registered enrollment target is 368 participants, below the 573-participant average among 28 other Corona Virus Infection trials with a reported enrollment target (36% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04342169, a Phase 2 study of Corona Virus Infection and Coronavirus, has completed, sponsored by University of Utah.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 368 participants
- Enrollment target
- 1
- Study location
Study Summary
A novel coronavirus, SARS-CoV-2, is responsible for a rapidly spreading pandemic that has reached 160 countries, infecting over 500,000 individuals and killing more than 24,000 people. SARS-CoV-2 causes an acute and potentially lethal respiratory illness, known as COVID-19, that is threatening to overwhelm health care systems due to a dramatic surge in hospitalized and critically ill patients. Patients hospitalized with COVID-19 typically have been symptomatic for 5-7 days prior to admission, indicating that there is a window during which an effective intervention could significantly alter the course of illness, lessen disease spread, and alleviate the stress on hospital resources. There is no known treatment for COVID-19, though in vitro and one poorly controlled study have identified a potential antiviral activity for HCQ. The rationale for this clinical trial is to measure the efficacy and safety of hydroxychloroquine for reducing viral load and shedding in adult outpatients with confirmed COVID-19.
Primary Outcome
Duration of viral shedding, as defined by time from randomization to the first of two consecutive negative swabs, measured on days 1 - 14.
Conditions Studied
Interventions
- DRUG Placebo oral tablet
- DRUG Hydroxychloroquine
Study Locations (1)
Utah
- University of Utah - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 368 participants |
| Start Date | 2020-04-04 |
| Est. Completion | 2021-11-15 |
| Phase | Phase 2 |
What the finished NCT04342169 record still lists
NCT04342169 is an interventional study that assigns participants to a tested intervention. The registered 368 participants enrollment target is mid-sized for trials with a published cap, below the 573-participant average among 28 other Corona Virus Infection trials with a reported enrollment target (36% lower).
The record links to 3 conditions, with Corona Virus Infection appearing as the primary indexed condition, and to 2 interventions - of which Placebo oral tablet is the first listed.
NCT04342169 reports a single indexed study location in Utah.
Frequently Asked Questions
What is clinical trial NCT04342169 about?
NCT04342169 is a clinical study titled "University of Utah COVID-19 Hydrochloroquine Trial". A novel coronavirus, SARS-CoV-2, is responsible for a rapidly spreading pandemic that has reached 160 countries, infecting over 500,000 individuals and killing more than 24,000 people. SARS-CoV-2 causes an acute and potentially lethal respiratory illness, known as COVID-19, that is threatening to ov...
What is the current status of trial NCT04342169?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 368 participants. The study started on 2020-04-04. Estimated completion is 2021-11-15.
What conditions does trial NCT04342169 study?
This clinical trial studies the following conditions: Corona Virus Infection, Coronavirus, Infectious Disease.
What interventions are being tested in trial NCT04342169?
The interventions under investigation include: Placebo oral tablet (DRUG), Hydroxychloroquine (DRUG).
Who is sponsoring clinical trial NCT04342169?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04342169 being conducted?
This trial has 1 study location across Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04342169's enrollment target sits among peer trials
368 8th of 28 higher than 21 of 28 other Corona Virus Infection trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Corona Virus Infection trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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