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NCT04339413 · ClinicalTrials.gov registry record · Phase 3

A Study to Evaluate the Safety and Tolerability of Long-term Administration of Gantenerumab in Participants With Alzheimer's Disease (AD)

A Phase 3 study, sponsored by Hoffmann-La Roche.

Terminated
Registry status
Phase 3
Development phase
116
Enrollment target

NCT04339413 is a Phase 3 study that was terminated before completion, run by Hoffmann-La Roche. The registered enrollment target is 116 participants.

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The verdict

NCT04339413, a Phase 3 study, was terminated before completion, sponsored by Hoffmann-La Roche.

TERMINATED
Registry status
Phase 3
Development phase
116 participants
Enrollment target

Study Summary

The main purpose of the study was to evaluate the safety and tolerability of long-term administration of gantenerumab in participants with AD. All participants who have completed the open-label extensions (OLEs) of studies WN25203 or WN28745 were enrolled in Part 1 of this study. Of these, participants who completed Week 104 visit in Part 1. Participants received open-label gantenerumab by subcutaneous (SC) injection every four weeks (Q4W) at the same dose as administered in the parent studies (part 1)/ Week 104 visit.

Interventions

  • DRUG Gantenerumab

Trial Details

FieldValue
Enrollment Target 116 participants
Start Date 2020-05-22
Est. Completion 2023-01-04
Phase Phase 3

Sponsor

Hoffmann-La Roche

909 total trials

What the Registry Record Tells You About NCT04339413

The ClinicalTrials.gov registry entry for NCT04339413 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 116 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hoffmann-La Roche, which has 909 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Gantenerumab is the first listed.

NCT04339413 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04339413 about?

NCT04339413 is a clinical study titled "A Study to Evaluate the Safety and Tolerability of Long-term Administration of Gantenerumab in Participants With Alzheimer's Disease (AD)". The main purpose of the study was to evaluate the safety and tolerability of long-term administration of gantenerumab in participants with AD. All participants who have completed the open-label extensions (OLEs) of studies WN25203 or WN28745 were enrolled in Part 1 of this study. Of these, participa...

What is the current status of trial NCT04339413?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 116 participants. The study started on 2020-05-22. Estimated completion is 2023-01-04.

What interventions are being tested in trial NCT04339413?

The interventions under investigation include: Gantenerumab (DRUG).

Who is sponsoring clinical trial NCT04339413?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.