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NCT04333732 · ClinicalTrials.gov registry record · Phase 3
CROWN CORONATION: COVID-19 Research Outcomes Worldwide Network for CORONAvirus prevenTION
A Phase 3 study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- Phase 3
- Development phase
- 3,411
- Enrollment target
NCT04333732: Completed Phase 3 study, sponsored by Washington University School of Medicine.
NCT04333732 is a Phase 3 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 3,411 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (342% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04333732, a Phase 3 study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 3,411 participants
- Enrollment target
Study Summary
The objective of CROWN CORONATION is the prevention of symptomatic COVID-19 by using combinations of approved and safe repurposed interventions, with complementary mechanisms of action.
Primary Outcome
Incidence of symptomatic (i.e. any of the following: cough, shortness of breath or difficulty breathing, fever, chills, muscle pain, sore throat, new loss of taste or smell, nausea, vomiting, or diarrhea), laboratory test-confirmed COVID-19 in the intervention and control groups in adults with repeated exposures to SARS-CoV-2 by day 60 after receiving trial intervention.
Interventions
- DRUG Placebo
- DRUG MR or M-M-R II ® vaccine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,411 participants |
| Start Date | 2020-09-04 |
| Est. Completion | 2021-12-03 |
| Phase | Phase 3 |
What the finished NCT04333732 record still lists
NCT04333732 is an interventional study that assigns participants to a tested intervention. Its 3,411 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (342% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04333732 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04333732 about?
NCT04333732 is a clinical study titled "CROWN CORONATION: COVID-19 Research Outcomes Worldwide Network for CORONAvirus prevenTION". The objective of CROWN CORONATION is the prevention of symptomatic COVID-19 by using combinations of approved and safe repurposed interventions, with complementary mechanisms of action.
What is the current status of trial NCT04333732?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 3,411 participants. The study started on 2020-09-04. Estimated completion is 2021-12-03.
What interventions are being tested in trial NCT04333732?
The interventions under investigation include: Placebo (DRUG), MR or M-M-R II ® vaccine (DRUG).
Who is sponsoring clinical trial NCT04333732?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04333732's enrollment target sits among peer trials
3,411 70th of 2000 higher than 1,931 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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