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NCT04318639 · ClinicalTrials.gov registry record · Phase 2
The Combination of Donepezil and Cognitive Training for Treating Alcohol Use Disorder
A Phase 2 study, sponsored by VA Connecticut Healthcare System.
- Completed
- Registry status
- Phase 2
- Development phase
- 15
- Enrollment target
NCT04318639: Completed Phase 2 study, sponsored by VA Connecticut Healthcare System.
NCT04318639 is a Phase 2 study that has completed, run by VA Connecticut Healthcare System. The registered enrollment target is 15 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04318639, a Phase 2 study, has completed, sponsored by VA Connecticut Healthcare System.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 15 participants
- Enrollment target
Study Summary
This is an open label feasibility trial to learn whether the combination of donepezil and cognitive remediation therapy (Donepezil + CRT) may improve neurocognitive functioning and decreasing alcohol use in Veterans with alcohol use disorder who have mild cognitive impairment (AUD-MCI). The study will determine the acceptability and adherence to treatment and preliminary evidence for efficacy. The study will recruit 15 newly recovering Veterans individuals with AUD-MCI for a 13-week, open-label, single-arm pilot study with sobriety and cognitive assessments at baseline and at 13-week follow-up.
Primary Outcome
7-point likert scale of recovery
Interventions
- COMBINATION_PRODUCT Donepazil
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2018-08-17 |
| Est. Completion | 2019-12-31 |
| Phase | Phase 2 |
What the finished NCT04318639 record still lists
NCT04318639 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower).
The record links to 0 conditions, and to 1 intervention - of which Donepazil is the first listed.
NCT04318639 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04318639 about?
NCT04318639 is a clinical study titled "The Combination of Donepezil and Cognitive Training for Treating Alcohol Use Disorder". This is an open label feasibility trial to learn whether the combination of donepezil and cognitive remediation therapy (Donepezil + CRT) may improve neurocognitive functioning and decreasing alcohol use in Veterans with alcohol use disorder who have mild cognitive impairment (AUD-MCI). The study wi...
What is the current status of trial NCT04318639?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2018-08-17. Estimated completion is 2019-12-31.
What interventions are being tested in trial NCT04318639?
The interventions under investigation include: Donepazil (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT04318639?
This trial is sponsored by VA Connecticut Healthcare System, which has 26 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04318639's enrollment target sits among peer trials
15 1919th of 2000 higher than 60 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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