Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04317495 · ClinicalTrials.gov registry record · NA
Augmenting rTMS With Cognitive Control Training in Major Depressive Disorder
A NA study, sponsored by University of Michigan.
- Terminated
- Registry status
- NA
- Development phase
- 4
- Enrollment target
NCT04317495: Clinical Trial NA study, sponsored by University of Michigan.
NCT04317495 is a NA study that was terminated before completion, run by University of Michigan. The registered enrollment target is 4 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04317495, a NA study, was terminated before completion, sponsored by University of Michigan.
- TERMINATED
- Registry status
- NA
- Development phase
- 4 participants
- Enrollment target
Study Summary
Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for MDD, but the overall effect sized of the treatment is equivalent to antidepressant pharmacotherapy, and responses are highly variable. Given that rTMS is usually given to patients who have failed pharmacotherapy, a more effective alternative is needed. Therefore, this study will combine computerized cognitive training (CCT) during standard rTMS treatments and assess its feasibility, tolerability, and changes in cognitive control performance and depression symptoms. Participants that agree to the study and meet eligibility will receive standard rTMS (generally 25-36 daily treatments) along with CCT (starting on day 5 of treatment until the pre-taper treatment). In addition, to CCT participants will be asked to complete assessments before and after treatment
Primary Outcome
Percentage CCT sessions completed: (number of sessions completed/number of sessions assigned) X 100
Interventions
- OTHER Computerized Cognitive Training (CCT)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2019-08-27 |
| Est. Completion | 2021-04-01 |
| Phase | NA |
Why NCT04317495 stopped before completion
NCT04317495 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Computerized Cognitive Training (CCT) is the first listed.
NCT04317495 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04317495 about?
NCT04317495 is a clinical study titled "Augmenting rTMS With Cognitive Control Training in Major Depressive Disorder". Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for MDD, but the overall effect sized of the treatment is equivalent to antidepressant pharmacotherapy, and responses are highly variable. Given that rTMS is usually given to patients who have failed pharmacotherapy, a mor...
What is the current status of trial NCT04317495?
This trial is currently terminated. It is a NA study. The enrollment target is 4 participants. The study started on 2019-08-27. Estimated completion is 2021-04-01.
What interventions are being tested in trial NCT04317495?
The interventions under investigation include: Computerized Cognitive Training (CCT) (OTHER).
Who is sponsoring clinical trial NCT04317495?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04317495's enrollment target sits among peer trials
4 1996th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI