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NCT04311177 · ClinicalTrials.gov registry record · Phase 2

Losartan for Patients With COVID-19 Not Requiring Hospitalization

A Phase 2 study, sponsored by University of Minnesota.

Completed
Registry status
Phase 2
Development phase
117
Enrollment target

NCT04311177: Completed Phase 2 study, sponsored by University of Minnesota.

NCT04311177 is a Phase 2 study that has completed, run by University of Minnesota. The registered enrollment target is 117 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (12% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04311177, a Phase 2 study, has completed, sponsored by University of Minnesota.

COMPLETED
Registry status
Phase 2
Development phase
117 participants
Enrollment target

Study Summary

This is a multi-center, double-blinded study of COVID-19 infected patients randomized 1:1 to daily losartan or placebo for 10 days or treatment failure (hospital admission).

Primary Outcome

Outcome reported as the percentage of participants per arm admitted to inpatient hospital care due to COVID-19-related disease within 15 days of randomization. Currently, there is a pre-planned pooled analysis with a national trial network under development.

Interventions

  • OTHER Placebo
  • DRUG Losartan

Trial Details

FieldValue
Enrollment Target 117 participants
Start Date 2020-04-09
Est. Completion 2021-02-01
Phase Phase 2
University of Minnesota

966 total trials

What the finished NCT04311177 record still lists

NCT04311177 is an interventional study that assigns participants to a tested intervention. The registered 117 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (12% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04311177 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04311177 about?

NCT04311177 is a clinical study titled "Losartan for Patients With COVID-19 Not Requiring Hospitalization". This is a multi-center, double-blinded study of COVID-19 infected patients randomized 1:1 to daily losartan or placebo for 10 days or treatment failure (hospital admission).

What is the current status of trial NCT04311177?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 117 participants. The study started on 2020-04-09. Estimated completion is 2021-02-01.

What interventions are being tested in trial NCT04311177?

The interventions under investigation include: Placebo (OTHER), Losartan (DRUG).

Who is sponsoring clinical trial NCT04311177?

This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04311177's enrollment target sits among peer trials

117 623rd of 2000 higher than 1,378 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04311177, the US trial registry maintained by the National Library of Medicine. NCT04311177 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.