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NCT04310735 · ClinicalTrials.gov registry record · NA
Examining Brain Responses Linked to Emotion in Individuals Who Smoke Cigarettes
A NA study, sponsored by Penn State University.
- Completed
- Registry status
- NA
- Development phase
- 62
- Enrollment target
NCT04310735: Completed NA study, sponsored by Penn State University.
NCT04310735 is a NA study that has completed, run by Penn State University. The registered enrollment target is 62 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04310735, a NA study, has completed, sponsored by Penn State University.
- COMPLETED
- Registry status
- NA
- Development phase
- 62 participants
- Enrollment target
Study Summary
The study will use functional magnetic resonance imaging and facial coding methods to study individuals who smoke cigarettes. Smoking expectancy (the extent to which one perceives an opportunity to smoke a cigarette) will be manipulated using instructions, and the investigators will examine the effects of this manipulation on two primary endpoints under conditions designed to induce an urge to smoke: (1) brain responses measured using fMRI and (2) subjective affective responses measured using facial coding. Secondary endpoints include self-report measures of the desire to smoke and current affect.
Primary Outcome
Blood-oxygen-level dependent (BOLD) signal measured using functional magnetic resonance imaging (fMRI) was analyzed as participants were presented with smoking-related and neutral cues. Following preprocessing with fMRIPrep (version 20.2.7), the FMRI Expert Analysis Tool (FEAT) from FMRIB's Software Library (FSL; version 6.0.7.4) was used to characterize brain activation differences in response to smoking-related versus neutral cues. Contrast of parameter estimate (COPE) values were calculated f
Interventions
- BEHAVIORAL Verbal smoking expectancy manipulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 62 participants |
| Start Date | 2019-10-04 |
| Est. Completion | 2023-11-28 |
| Phase | NA |
What the finished NCT04310735 record still lists
NCT04310735 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 62 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 1 intervention - of which Verbal smoking expectancy manipulation is the first listed.
NCT04310735 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04310735 about?
NCT04310735 is a clinical study titled "Examining Brain Responses Linked to Emotion in Individuals Who Smoke Cigarettes". The study will use functional magnetic resonance imaging and facial coding methods to study individuals who smoke cigarettes. Smoking expectancy (the extent to which one perceives an opportunity to smoke a cigarette) will be manipulated using instructions, and the investigators will examine the effe...
What is the current status of trial NCT04310735?
This trial is currently completed. It is a NA study. The enrollment target is 62 participants. The study started on 2019-10-04. Estimated completion is 2023-11-28.
What interventions are being tested in trial NCT04310735?
The interventions under investigation include: Verbal smoking expectancy manipulation (BEHAVIORAL).
Who is sponsoring clinical trial NCT04310735?
This trial is sponsored by Penn State University, which has 219 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04310735's enrollment target sits among peer trials
62 1157th of 2000 higher than 837 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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