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NCT04296006 · ClinicalTrials.gov registry record · Early Phase 1
Neurobehavioral Mechanisms of Cocaine Choice
A Early Phase 1 study, sponsored by Joshua A. Lile, Ph.D..
- Completed
- Registry status
- Early Phase 1
- Development phase
- 15
- Enrollment target
NCT04296006: Completed Early Phase 1 study, sponsored by Joshua A. Lile, Ph.D..
NCT04296006 is a Early Phase 1 study that has completed, run by Joshua A. Lile, Ph.D.. The registered enrollment target is 15 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04296006, a Early Phase 1 study, has completed, sponsored by Joshua A. Lile, Ph.D..
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 15 participants
- Enrollment target
Study Summary
The objective of this protocol is to use a drug-vs-money choice task, reinforcement learning modeling and fMRI to determine the neurobehavioral and neurobiological decision-making "profile" associated with the decision to take cocaine and the reduced cocaine choice that occurs during a behavioral intervention (alternative money reinforcer) that models contingency management.
Primary Outcome
The reinforcing effects of cocaine are determined using a reinforcement learning choice task. Subjects complete trials in which they could possibly receive the available cocaine dose or money. Reinforcing effects are measured for a fixed cocaine dose when three amounts of money are available as alternatives to cocaine. Each money value is tested in a separate session.
Interventions
- BEHAVIORAL Money
- DRUG Cocaine HCl
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2021-01-15 |
| Est. Completion | 2025-02-01 |
| Phase | Early Phase 1 |
What the finished NCT04296006 record still lists
NCT04296006 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (72% lower).
The record links to 0 conditions, and to 2 interventions - of which Money is the first listed.
NCT04296006 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04296006 about?
NCT04296006 is a clinical study titled "Neurobehavioral Mechanisms of Cocaine Choice". The objective of this protocol is to use a drug-vs-money choice task, reinforcement learning modeling and fMRI to determine the neurobehavioral and neurobiological decision-making "profile" associated with the decision to take cocaine and the reduced cocaine choice that occurs during a behavioral in...
What is the current status of trial NCT04296006?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 15 participants. The study started on 2021-01-15. Estimated completion is 2025-02-01.
What interventions are being tested in trial NCT04296006?
The interventions under investigation include: Money (BEHAVIORAL), Cocaine HCl (DRUG).
Who is sponsoring clinical trial NCT04296006?
This trial is sponsored by Joshua A. Lile, Ph.D., which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04296006's enrollment target sits among peer trials
15 1403rd of 2000 higher than 527 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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