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NCT04285515 · ClinicalTrials.gov registry record · Phase 3

Clinical Trial Evaluating Lumateperone Monotherapy in the Treatment of Bipolar Depression or Major Depressive Disorder

A Phase 3 study, sponsored by Intra-Cellular Therapies.

Completed
Registry status
Phase 3
Development phase
488
Enrollment target

NCT04285515 is a Phase 3 study that has completed, run by Intra-Cellular Therapies. The registered enrollment target is 488 participants.

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The verdict

NCT04285515, a Phase 3 study, has completed, sponsored by Intra-Cellular Therapies.

COMPLETED
Registry status
Phase 3
Development phase
488 participants
Enrollment target

Study Summary

This is a randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of lumateperone monotherapy in the treatment of patients with major depressive episodes associated with Bipolar I or Bipolar II Disorder (Bipolar Depression) or major depressive disorder (MDD) who also meet the Diagnostic and Statistical Manual of Mental Disorder, 5th Edition (DSM-5) criteria for mixed-features. The study consists of a Screening Period, a Double-blind Treatment Period, and a Safety Follow-up Period.

Interventions

  • DRUG Lumateperone
  • DRUG Placebos

Trial Details

FieldValue
Enrollment Target 488 participants
Start Date 2020-02-27
Est. Completion 2022-11-30
Phase Phase 3

Sponsor

Intra-Cellular Therapies

37 total trials

What the Registry Record Tells You About NCT04285515

The ClinicalTrials.gov registry entry for NCT04285515 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 488 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Intra-Cellular Therapies, which has 37 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Lumateperone is the first listed.

NCT04285515 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04285515 about?

NCT04285515 is a clinical study titled "Clinical Trial Evaluating Lumateperone Monotherapy in the Treatment of Bipolar Depression or Major Depressive Disorder". This is a randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of lumateperone monotherapy in the treatment of patients with major depressive episodes associated with Bipolar I or Bipolar II Disorder (Bipolar Depression) or major depressive disorder (MD...

What is the current status of trial NCT04285515?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 488 participants. The study started on 2020-02-27. Estimated completion is 2022-11-30.

What interventions are being tested in trial NCT04285515?

The interventions under investigation include: Lumateperone (DRUG), Placebos (DRUG).

Who is sponsoring clinical trial NCT04285515?

This trial is sponsored by Intra-Cellular Therapies, which has 37 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.