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NCT04282889 · ClinicalTrials.gov registry record
Rotational Thromboelastometry (ROTEM) TRUE-NATEM Reference Value Validation in Liver Transplantation
A clinical trial, sponsored by Thomas Jefferson University.
- Completed
- Registry status
- 40
- Enrollment target
NCT04282889: Completed study, sponsored by Thomas Jefferson University.
NCT04282889 is a clinical trial that has completed, run by Thomas Jefferson University. The registered enrollment target is 40 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04282889 has completed, sponsored by Thomas Jefferson University.
- COMPLETED
- Registry status
- 40 participants
- Enrollment target
Study Summary
Background: Rotational thromboelastometry (ROTEM) has been used widely in liver transplantation for coagulation management. However, a TRUE-NATEM (TRUE-Non-Activated Rotational Thromboelastometry) reference value has never been established. A TRUE-NATEM value is of clinical significance since no coagulation activators or reagents will be added to the blood sample for analysis. Therefore, the result will reflect the true coagulation profile of the patient. Methods: Non-citrated whole blood will be used for analysis. Blood will be drawn from the patient and transferred into a plastic reagent cup that has no reagent. Test will be performed within 4 minutes of blood draw to avoid activation of coagulation. Primary outcome measure will be clotting time (CT), clot formation time (CFT) and maximum clot firmness (MCF). The specific aims of the study are to establish a TRUE-NATEM reference value using Rotational Thromboelastometry (ROTEM®) in patients undergoing liver transplantation. Our hypothesis is that clotting time (CT), clot formation time (CFT) is prolonged and maximum clot firmness (MCF) decreased compared to healthy volunteers in patient undergoing liver transplantation due to synthetic coagulation factor deficiency.
Primary Outcome
clotting time (CT) in seconds
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2020-10-06 |
| Est. Completion | 2021-02-01 |
What the finished NCT04282889 record still lists
NCT04282889 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT04282889 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04282889 about?
NCT04282889 is a clinical study titled "Rotational Thromboelastometry (ROTEM) TRUE-NATEM Reference Value Validation in Liver Transplantation". Background: Rotational thromboelastometry (ROTEM) has been used widely in liver transplantation for coagulation management. However, a TRUE-NATEM (TRUE-Non-Activated Rotational Thromboelastometry) reference value has never been established. A TRUE-NATEM value is of clinical significance since no coa...
What is the current status of trial NCT04282889?
This trial is currently completed. The enrollment target is 40 participants. The study started on 2020-10-06. Estimated completion is 2021-02-01.
Who is sponsoring clinical trial NCT04282889?
This trial is sponsored by Thomas Jefferson University, which has 292 total clinical trials registered on ClinicalTrials.gov.
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