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NCT04279392 · ClinicalTrials.gov registry record · Phase 1
Healthy Body, Healthy Bones After Bariatric Surgery Trial
A Phase 1 study, sponsored by University of Nebraska.
- Completed
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
NCT04279392: Completed Phase 1 study, sponsored by University of Nebraska.
NCT04279392 is a Phase 1 study that has completed, run by University of Nebraska. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04279392, a Phase 1 study, has completed, sponsored by University of Nebraska.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
Study Summary
One in three adults in the United States suffers from obesity. Bariatric surgery is an increasingly utilized and effective treatment for obesity and obesity-related comorbidities, however, the massive weight loss associated with bariatric surgery adversely affects bone leads to an increased risk of fracture. Bisphosphonate medications, such as zoledronic acid, are used to treat bone loss in patients with osteoporosis, and this study investigates whether this medication can prevent bone loss associated with surgical weight loss procedures.
Primary Outcome
Change in hip bone mineral density (BMD) measured by dual-energy x-ray absorptiometry (DXA) - g/cm2
Interventions
- DRUG Placebos
- DRUG Zoledronic Acid 5 mg/Bag 100 ml Inj
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2020-09-01 |
| Est. Completion | 2022-12-30 |
| Phase | Phase 1 |
What the finished NCT04279392 record still lists
NCT04279392 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebos is the first listed.
NCT04279392 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04279392 about?
NCT04279392 is a clinical study titled "Healthy Body, Healthy Bones After Bariatric Surgery Trial". One in three adults in the United States suffers from obesity. Bariatric surgery is an increasingly utilized and effective treatment for obesity and obesity-related comorbidities, however, the massive weight loss associated with bariatric surgery adversely affects bone leads to an increased risk of ...
What is the current status of trial NCT04279392?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2020-09-01. Estimated completion is 2022-12-30.
What interventions are being tested in trial NCT04279392?
The interventions under investigation include: Placebos (DRUG), Zoledronic Acid 5 mg/Bag 100 ml Inj (DRUG).
Who is sponsoring clinical trial NCT04279392?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04279392's enrollment target sits among peer trials
10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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