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NCT04278053 · ClinicalTrials.gov registry record · NA
Evaluation of Sports Supplements on Blood Flow
A NA study, sponsored by University of Arkansas, Fayetteville.
- Completed
- Registry status
- NA
- Development phase
- 24
- Enrollment target
NCT04278053: Completed NA study, sponsored by University of Arkansas, Fayetteville.
NCT04278053 is a NA study that has completed, run by University of Arkansas, Fayetteville. The registered enrollment target is 24 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04278053, a NA study, has completed, sponsored by University of Arkansas, Fayetteville.
- COMPLETED
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
Study Summary
Many athletes seek to increase their plasma (blood) nitric oxide content prior to exercise in order to augment vasodilation. Increased vasodilation during exercise, especially high intensity resistance training, allows for more blood flow to muscle tissues, which may give the athlete benefits such as increased work capacity and acute muscle hyperemia, which is commonly referred to as muscle pump. Pre-workout supplements are typically taken 30 minutes to 1 hour prior to the onset of exercise, so the current investigation seeks to determine if citrulline malate or nitrosigine can effect vasodilation within 1 hour of supplementation, and if so, which supplement is more effective. Based on previous findings, we hypothesize that a certain exercise intensity needs to be present for citrulline malate and nitrosigine to have an effect, so a change may not be observable at rest.
Primary Outcome
Amount of brachial vasodilation caused by supplementation as measured by flow-mediated dilation and ultrasound
Interventions
- DIETARY_SUPPLEMENT inositol-stabilized arginine silicate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2018-10-15 |
| Est. Completion | 2019-05-08 |
| Phase | NA |
What the finished NCT04278053 record still lists
NCT04278053 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which inositol-stabilized arginine silicate is the first listed.
NCT04278053 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04278053 about?
NCT04278053 is a clinical study titled "Evaluation of Sports Supplements on Blood Flow". Many athletes seek to increase their plasma (blood) nitric oxide content prior to exercise in order to augment vasodilation. Increased vasodilation during exercise, especially high intensity resistance training, allows for more blood flow to muscle tissues, which may give the athlete benefits such a...
What is the current status of trial NCT04278053?
This trial is currently completed. It is a NA study. The enrollment target is 24 participants. The study started on 2018-10-15. Estimated completion is 2019-05-08.
What interventions are being tested in trial NCT04278053?
The interventions under investigation include: inositol-stabilized arginine silicate (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT04278053?
This trial is sponsored by University of Arkansas, Fayetteville, which has 25 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04278053's enrollment target sits among peer trials
24 1736th of 2000 higher than 246 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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