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NCT04273841 · ClinicalTrials.gov registry record · NA
Impact of Sleep Deprivation and Caffeine in Medical Professionals
A NA study, sponsored by Walter Reed Army Institute of Research (WRAIR).
- Terminated
- Registry status
- NA
- Development phase
- 7
- Enrollment target
NCT04273841 is a NA study that was terminated before completion, run by Walter Reed Army Institute of Research (WRAIR). The registered enrollment target is 7 participants.
The verdict
NCT04273841, a NA study, was terminated before completion, sponsored by Walter Reed Army Institute of Research (WRAIR).
- TERMINATED
- Registry status
- NA
- Development phase
- 7 participants
- Enrollment target
Study Summary
While the negative impact of sleep deprivation on cognitive processing and the partial reversal of this phenomenon by caffeine are well known, the types of cognitive processing previously studied have been limited to simple, straight-forward laboratory tasks. It is unclear how sleep deprivation and caffeine affect performance on operationally relevant complex cognitive tasks, like those encountered by working professionals such as doctors. This study aims to uncover how sleep deprivation and caffeine impact two types of clinical reasoning processes encountered by physicians on a daily basis. Previous work from members of our team investigated diagnostic reasoning in medical professionals and discovered that brain activation in executive processing areas was modulated by self-reported sleepiness and burnout and level of expertise (Durning, Costanzo, et al., 2013; Durning et al., 2014, 2015). The current study aims to expand upon those findings by also investigating a potentially more complex type of clinical reasoning, i.e. therapeutic reasoning, and directly manipulating sleep and caffeine use in a controlled sleep laboratory. Medical students, residents, and board-certified physicians will undergo thirty-seven hours of sleep deprivation and ten hours of sleep recovery in the sleep laboratory. During two FMRI scan sessions we will present high-quality validated multiple-choice questions on common patient situations in internal medicine to participants to explore brain activity during therapeutic reasoning compared with diagnostic reasoning. One FMRI scan will occur following a night of sleep deprivation, and another scan will occur following a night of recovery sleep. Additionally, half of the participants will receive caffeine gum during the sleep deprivation period, while the other half will receive placebo gum. This design will allow us to study the effect of sleep deprivation and caffeine on the neural correlates of diagnostic and therapeutic reasoning and perfo
Interventions
- DIETARY_SUPPLEMENT Military Energy Gum
- DIETARY_SUPPLEMENT Placebo Gum
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2017-07-06 |
| Est. Completion | 2024-07-09 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04273841
The ClinicalTrials.gov registry entry for NCT04273841 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 7 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Walter Reed Army Institute of Research (WRAIR), which has 12 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Military Energy Gum is the first listed.
NCT04273841 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04273841 about?
NCT04273841 is a clinical study titled "Impact of Sleep Deprivation and Caffeine in Medical Professionals". While the negative impact of sleep deprivation on cognitive processing and the partial reversal of this phenomenon by caffeine are well known, the types of cognitive processing previously studied have been limited to simple, straight-forward laboratory tasks. It is unclear how sleep deprivation and ...
What is the current status of trial NCT04273841?
This trial is currently terminated. It is a NA study. The enrollment target is 7 participants. The study started on 2017-07-06. Estimated completion is 2024-07-09.
What interventions are being tested in trial NCT04273841?
The interventions under investigation include: Military Energy Gum (DIETARY_SUPPLEMENT), Placebo Gum (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT04273841?
This trial is sponsored by Walter Reed Army Institute of Research (WRAIR), which has 12 total clinical trials registered on ClinicalTrials.gov.
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