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NCT04271475 · ClinicalTrials.gov registry record · Phase 3

A Study to Evaluate Efficacy and Safety of Macitentan 75 mg in Inoperable or Persistent/Recurrent Chronic Thromboembolic Pulmonary Hypertension

A Phase 3 study, sponsored by Actelion.

Terminated
Registry status
Phase 3
Development phase
127
Enrollment target

NCT04271475 is a Phase 3 study that was terminated before completion, run by Actelion. The registered enrollment target is 127 participants.

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The verdict

NCT04271475, a Phase 3 study, was terminated before completion, sponsored by Actelion.

TERMINATED
Registry status
Phase 3
Development phase
127 participants
Enrollment target

Study Summary

The purpose of the study is to evaluate the effect of macitentan 75 mg versus placebo on exercise capacity at Week 28 in participants with chronic thromboembolic pulmonary hypertension (CTEPH).

Interventions

  • DRUG Placebo
  • DRUG Macitentan

Trial Details

FieldValue
Enrollment Target 127 participants
Start Date 2020-07-07
Est. Completion 2023-12-21
Phase Phase 3

Sponsor

Actelion

63 total trials

What the Registry Record Tells You About NCT04271475

The ClinicalTrials.gov registry entry for NCT04271475 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 127 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Actelion, which has 63 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04271475 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04271475 about?

NCT04271475 is a clinical study titled "A Study to Evaluate Efficacy and Safety of Macitentan 75 mg in Inoperable or Persistent/Recurrent Chronic Thromboembolic Pulmonary Hypertension". The purpose of the study is to evaluate the effect of macitentan 75 mg versus placebo on exercise capacity at Week 28 in participants with chronic thromboembolic pulmonary hypertension (CTEPH).

What is the current status of trial NCT04271475?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 127 participants. The study started on 2020-07-07. Estimated completion is 2023-12-21.

What interventions are being tested in trial NCT04271475?

The interventions under investigation include: Placebo (DRUG), Macitentan (DRUG).

Who is sponsoring clinical trial NCT04271475?

This trial is sponsored by Actelion, which has 63 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.