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NCT04265807 · ClinicalTrials.gov registry record · NA
Remote Ischemic Conditioning to Enhance Resuscitation (RICE) Pilot
A NA study, sponsored by University of Washington.
- Completed
- Registry status
- NA
- Development phase
- 30
- Enrollment target
NCT04265807: Completed NA study, sponsored by University of Washington.
NCT04265807 is a NA study that has completed, run by University of Washington. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04265807, a NA study, has completed, sponsored by University of Washington.
- COMPLETED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
Study Summary
Following resuscitation from out-of-hospital cardiac arrest (OHCA), reperfusion injury can cause cell damage in the heart and brain. Remote ischemic conditioning (RIC) consists of intermittent application of a device such as a blood pressure cuff to a limb to induce non-lethal ischemia. Studies in animals with cardiac arrest as well as in humans with acute myocardial infarction suggest that RIC before or after restoration of blood flow may reduce injury to the heart and improve outcomes but this has not been proven in humans who have had OHCA. The RICE pilot study is a single-center study to assess the feasibility of application of RIC in the emergency department setting for patients transported to the hospital after resuscitation from OHCA.
Primary Outcome
Attrition assessed as the proportion of randomized subjects who do not remain on allocated therapy for the intended study duration among subjects randomly allocated. On therapy for the intended study duration consists of completing three cycles of inflation-deflation.
Interventions
- DEVICE Active Remote Ischemic Conditioning
- DEVICE Sham Remote Ischemic Conditioning
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2020-07-01 |
| Est. Completion | 2022-02-03 |
| Phase | NA |
What the finished NCT04265807 record still lists
NCT04265807 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Active Remote Ischemic Conditioning is the first listed.
NCT04265807 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04265807 about?
NCT04265807 is a clinical study titled "Remote Ischemic Conditioning to Enhance Resuscitation (RICE) Pilot". Following resuscitation from out-of-hospital cardiac arrest (OHCA), reperfusion injury can cause cell damage in the heart and brain. Remote ischemic conditioning (RIC) consists of intermittent application of a device such as a blood pressure cuff to a limb to induce non-lethal ischemia. Studies in a...
What is the current status of trial NCT04265807?
This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2020-07-01. Estimated completion is 2022-02-03.
What interventions are being tested in trial NCT04265807?
The interventions under investigation include: Active Remote Ischemic Conditioning (DEVICE), Sham Remote Ischemic Conditioning (DEVICE).
Who is sponsoring clinical trial NCT04265807?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04265807's enrollment target sits among peer trials
30 1593rd of 2000 higher than 299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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