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NCT04250194 · ClinicalTrials.gov registry record · NA
Navigation Endoscopy to Reach Indeterminate Lung Nodules Versus Trans-Thoracic Needle Aspiration
A NA study of Lung Nodule, sponsored by Vanderbilt-Ingram Cancer Center.
- Completed
- Registry status
- NA
- Development phase
- 288
- Enrollment target
- 7
- Study locations
NCT04250194: Completed NA study of Lung Nodule, sponsored by Vanderbilt-Ingram Cancer Center.
NCT04250194 is a NA study of Lung Nodule that has completed, run by Vanderbilt-Ingram Cancer Center. The registered enrollment target is 288 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (79% lower). The trial reports 7 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04250194, a NA study of Lung Nodule, has completed, sponsored by Vanderbilt-Ingram Cancer Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 288 participants
- Enrollment target
- 7
- Study locations
Study Summary
This study will evaluate which procedure is the best for patients referred for biopsy of a lung nodule (growth in the lung) meeting the size and location requirements of the protocol. Two different procedures are available for lung nodule biopsy: 1. a computed tomography guided biopsy ("CT-guided biopsy") which consists of sampling the nodule from the "outside-in", through the chest wall with CT guidance, and 2. navigation bronchoscopy, which is a procedure using technology designed to guide a catheter through the natural airway route (wind-pipe and bronchi) to access the nodule.
Primary Outcome
Proportion of biopsies leading to a definitive diagnosis, comparing the bronchoscopy pathway to the CT-guided biopsy pathway. Definitive diagnoses are pre-defined as any of the following: * Malignant, OR * Abnormal tissue (excluding normal or absence of lung parenchyma) followed by a surgical lung biopsy yielding the same histological diagnosis, OR * Specific benign histopathologic finding which accounts for the presence of a lung nodule (specifically including organizing pneumonia, frank purul
Conditions Studied
Interventions
- DEVICE CT-Guided Biopsy
- DEVICE Navigation bronchoscopy
Study Locations (7)
California
- University of California, San Diego - San Diego
Idaho
- Kootenai Health - Coeur d'Alene
Illinois
- Rush University Medical Center - Chicago
Missouri
- Saint Luke's Hospital of Kansas City - Kansas City
North Carolina
- Duke University Medical Center - Durham
Tennessee
- Vanderbilt-Ingram Cancer Center - Nashville
Wisconsin
- Medical College of Wisconsin - Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 288 participants |
| Start Date | 2020-05-22 |
| Est. Completion | 2024-07-02 |
| Phase | NA |
What the finished NCT04250194 record still lists
NCT04250194 is an interventional study that assigns participants to a tested intervention. The registered 288 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (79% lower).
The record links to 1 condition, with Lung Nodule appearing as the primary indexed condition, and to 2 interventions - of which CT-Guided Biopsy is the first listed.
NCT04250194 lists 7 locations in 7 states (California, Idaho, Illinois).
Frequently Asked Questions
What is clinical trial NCT04250194 about?
NCT04250194 is a clinical study titled "Navigation Endoscopy to Reach Indeterminate Lung Nodules Versus Trans-Thoracic Needle Aspiration". This study will evaluate which procedure is the best for patients referred for biopsy of a lung nodule (growth in the lung) meeting the size and location requirements of the protocol. Two different procedures are available for lung nodule biopsy: 1. a computed tomography guided biopsy ("CT-guided b...
What is the current status of trial NCT04250194?
This trial is currently completed. It is a NA study. The enrollment target is 288 participants. The study started on 2020-05-22. Estimated completion is 2024-07-02.
What conditions does trial NCT04250194 study?
This clinical trial studies the following conditions: Lung Nodule.
What interventions are being tested in trial NCT04250194?
The interventions under investigation include: CT-Guided Biopsy (DEVICE), Navigation bronchoscopy (DEVICE).
Who is sponsoring clinical trial NCT04250194?
This trial is sponsored by Vanderbilt-Ingram Cancer Center, which has 189 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04250194 being conducted?
This trial has 7 study locations across California, Idaho, Illinois, Missouri, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04250194's enrollment target sits among peer trials
288 376th of 2000 higher than 1,624 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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