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NCT04249947 · ClinicalTrials.gov registry record · Phase 1
P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)
A Phase 1 study, sponsored by Poseida Therapeutics.
- Terminated
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
NCT04249947: Clinical Trial Phase 1 study, sponsored by Poseida Therapeutics.
NCT04249947 is a Phase 1 study that was terminated before completion, run by Poseida Therapeutics. The registered enrollment target is 40 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04249947, a Phase 1 study, was terminated before completion, sponsored by Poseida Therapeutics.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
Study Summary
An open-label, multi-center, single and cyclic ascending dose study of P-PSMA-101 autologous CAR-T cells in patients with mCRPC and SGC.
Primary Outcome
Incidence and severity of treatment-emergent adverse events
Interventions
- DRUG Rimiducid
- BIOLOGICAL P-PSMA-101 CAR-T cells
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2020-02-28 |
| Est. Completion | 2024-09-30 |
| Phase | Phase 1 |
Why NCT04249947 stopped before completion
NCT04249947 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower).
The record links to 0 conditions, and to 2 interventions - of which Rimiducid is the first listed.
NCT04249947 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04249947 about?
NCT04249947 is a clinical study titled "P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)". An open-label, multi-center, single and cyclic ascending dose study of P-PSMA-101 autologous CAR-T cells in patients with mCRPC and SGC.
What is the current status of trial NCT04249947?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2020-02-28. Estimated completion is 2024-09-30.
What interventions are being tested in trial NCT04249947?
The interventions under investigation include: Rimiducid (DRUG), P-PSMA-101 CAR-T cells (BIOLOGICAL).
Who is sponsoring clinical trial NCT04249947?
This trial is sponsored by Poseida Therapeutics, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04249947's enrollment target sits among peer trials
40 1130th of 2000 higher than 810 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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