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NCT04246476 · ClinicalTrials.gov registry record · NA

Sing for Your Saunter

A NA study, sponsored by Washington University School of Medicine.

Completed
Registry status
NA
Development phase
67
Enrollment target

NCT04246476: Completed NA study, sponsored by Washington University School of Medicine.

NCT04246476 is a NA study that has completed, run by Washington University School of Medicine. The registered enrollment target is 67 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04246476, a NA study, has completed, sponsored by Washington University School of Medicine.

COMPLETED
Registry status
NA
Development phase
67 participants
Enrollment target

Study Summary

Older adults, and particularly those with Parkinson disease (PD), may experience walking difficulties that negatively impact their daily function and quality of life. This project will examine the impact of music and mentally singing on walking performance, with a goal of understanding what types of rhythmic cues are most helpful. Our pilot work suggests that imagined, mental singing (i.e., singing in your head) while while walking helps people walk faster with greater stability, whereas walking to music also helps people walk faster but with reduced stability. In Aim 1, the investigators will compare walking while mentally singing to walking while listening to music, using personalized cues tailored to each person's walking performance. The investigators hypothesize stride time variability will be less in the mental singing condition compared to listening to music; and that mental singing and listening to music will improve gait speed similarly as compared to the uncued condition. The investigators will also test whether finger tapping, a rhythmic task similar to walking in many ways, responds similarly while mentally singing and listening to music. In Aim 2, the investigator will investigate the brain mechanisms underlying the enhancements in movement performance seen with mental signing or listening to music. The investigators will use magnetic resonance imaging (MRI) to measure brain activity during finger tapping with and without various cues to understand which areas of the brain are more or less responsive to the cues. The investigators hypothesize individuals with PD will exhibit lesser activation of putamen and greater activation of cortical motor areas and cerebellum compared to controls in all tapping conditions; and internal, mental singing during tapping will elicit greater activation of the putamen and lesser activation of cortical motor areas in both groups compared to uncued tapping and tapping while listening to music.

Primary Outcome

Measured with wearable sensors by APDM Wearable Technology

Interventions

  • BEHAVIORAL Listening to music
  • BEHAVIORAL Mentally singing

Trial Details

FieldValue
Enrollment Target 67 participants
Start Date 2020-03-09
Est. Completion 2023-01-20
Phase NA

What the finished NCT04246476 record still lists

NCT04246476 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 67 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 2 interventions - of which Listening to music is the first listed.

NCT04246476 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04246476 about?

NCT04246476 is a clinical study titled "Sing for Your Saunter". Older adults, and particularly those with Parkinson disease (PD), may experience walking difficulties that negatively impact their daily function and quality of life. This project will examine the impact of music and mentally singing on walking performance, with a goal of understanding what types of...

What is the current status of trial NCT04246476?

This trial is currently completed. It is a NA study. The enrollment target is 67 participants. The study started on 2020-03-09. Estimated completion is 2023-01-20.

What interventions are being tested in trial NCT04246476?

The interventions under investigation include: Listening to music (BEHAVIORAL), Mentally singing (BEHAVIORAL).

Who is sponsoring clinical trial NCT04246476?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04246476's enrollment target sits among peer trials

67 1139th of 2000 higher than 862 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04246476, the US trial registry maintained by the National Library of Medicine. NCT04246476 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.