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NCT04235140 · ClinicalTrials.gov registry record · Phase 3

Long-term Safety of Lumacaftor/Ivacaftor in Participants With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation

A Phase 3 study, sponsored by Vertex Pharmaceuticals Incorporated.

Completed
Registry status
Phase 3
Development phase
52
Enrollment target

NCT04235140 is a Phase 3 study that has completed, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 52 participants.

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The verdict

NCT04235140, a Phase 3 study, has completed, sponsored by Vertex Pharmaceuticals Incorporated.

COMPLETED
Registry status
Phase 3
Development phase
52 participants
Enrollment target

Study Summary

This is a Phase 3, multicenter, open-label and roll-over study in participants who are 12 to \<24 months of age at initiation of Lumacaftor/Ivacaftor (LUM/IVA) treatment.

Interventions

  • DRUG LUM/IVA

Trial Details

FieldValue
Enrollment Target 52 participants
Start Date 2020-02-24
Est. Completion 2023-08-22
Phase Phase 3

Sponsor

Vertex Pharmaceuticals Incorporated

191 total trials

What the Registry Record Tells You About NCT04235140

The ClinicalTrials.gov registry entry for NCT04235140 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vertex Pharmaceuticals Incorporated, which has 191 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which LUM/IVA is the first listed.

NCT04235140 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04235140 about?

NCT04235140 is a clinical study titled "Long-term Safety of Lumacaftor/Ivacaftor in Participants With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation". This is a Phase 3, multicenter, open-label and roll-over study in participants who are 12 to \<24 months of age at initiation of Lumacaftor/Ivacaftor (LUM/IVA) treatment.

What is the current status of trial NCT04235140?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 52 participants. The study started on 2020-02-24. Estimated completion is 2023-08-22.

What interventions are being tested in trial NCT04235140?

The interventions under investigation include: LUM/IVA (DRUG).

Who is sponsoring clinical trial NCT04235140?

This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.