Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04230681 · ClinicalTrials.gov registry record · Early Phase 1
Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy Surgery
A Early Phase 1 study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 189
- Enrollment target
NCT04230681: Completed Early Phase 1 study, sponsored by Washington University School of Medicine.
NCT04230681 is a Early Phase 1 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 189 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (257% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04230681, a Early Phase 1 study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 189 participants
- Enrollment target
Study Summary
A RCT to compare hydromorphone versus fentanyl for pain control following tonsillectomy or adenotonsillectomy surgery.
Primary Outcome
Number
Interventions
- DRUG Hydromorphone
- DRUG Fentanyl
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 189 participants |
| Start Date | 2020-02-26 |
| Est. Completion | 2022-04-01 |
| Phase | Early Phase 1 |
What the finished NCT04230681 record still lists
NCT04230681 is an interventional study that assigns participants to a tested intervention. The registered 189 participants enrollment target is mid-sized for trials with a published cap, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (257% higher).
The record links to 0 conditions, and to 2 interventions - of which Hydromorphone is the first listed.
NCT04230681 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04230681 about?
NCT04230681 is a clinical study titled "Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy Surgery". A RCT to compare hydromorphone versus fentanyl for pain control following tonsillectomy or adenotonsillectomy surgery.
What is the current status of trial NCT04230681?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 189 participants. The study started on 2020-02-26. Estimated completion is 2022-04-01.
What interventions are being tested in trial NCT04230681?
The interventions under investigation include: Hydromorphone (DRUG), Fentanyl (DRUG).
Who is sponsoring clinical trial NCT04230681?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04230681's enrollment target sits among peer trials
189 74th of 2000 higher than 1,927 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02734537 · 189 participants · Phase 2
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
- NCT05058651 · 189 participants · Phase 2
Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung
- NCT05673408 · 189 participants
NIBP Validation Study
- NCT05994209 · 189 participants · Phase 1
Testing the Feasibility and Acceptability of Social Media and Digital Therapeutics to Decrease Vaping Behaviors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI