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NCT04230213 · ClinicalTrials.gov registry record · Phase 3
A Comparative Study Between PF-06410293 and Humira® in Combination With Methotrexate in Participants With Active Rheumatoid Arthritis
A Phase 3 study, sponsored by Pfizer.
- Completed
- Registry status
- Phase 3
- Development phase
- 455
- Enrollment target
NCT04230213: Completed Phase 3 study, sponsored by Pfizer.
NCT04230213 is a Phase 3 study that has completed, run by Pfizer. The registered enrollment target is 455 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (41% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04230213, a Phase 3 study, has completed, sponsored by Pfizer.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 455 participants
- Enrollment target
Study Summary
The study will assess the impact of pharmacokinetics (PK), safety and immunogenicity after switches between PF-06410293 and adalimumab and with continuous dosing with adalimumab in combination with methotrexate in subjects with moderately to severely active rheumatoid arthritis.
Primary Outcome
Cmax refers to maximum observed serum concentration of drug. The geometric coefficient of variation is expressed in percentage.
Interventions
- DRUG adalimumab
- DRUG PF-06410293
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 455 participants |
| Start Date | 2020-01-13 |
| Est. Completion | 2021-06-22 |
| Phase | Phase 3 |
What the finished NCT04230213 record still lists
NCT04230213 is an interventional study that assigns participants to a tested intervention. The registered 455 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (41% lower).
The record links to 0 conditions, and to 2 interventions - of which adalimumab is the first listed.
NCT04230213 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04230213 about?
NCT04230213 is a clinical study titled "A Comparative Study Between PF-06410293 and Humira® in Combination With Methotrexate in Participants With Active Rheumatoid Arthritis". The study will assess the impact of pharmacokinetics (PK), safety and immunogenicity after switches between PF-06410293 and adalimumab and with continuous dosing with adalimumab in combination with methotrexate in subjects with moderately to severely active rheumatoid arthritis.
What is the current status of trial NCT04230213?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 455 participants. The study started on 2020-01-13. Estimated completion is 2021-06-22.
What interventions are being tested in trial NCT04230213?
The interventions under investigation include: adalimumab (DRUG), PF-06410293 (DRUG).
Who is sponsoring clinical trial NCT04230213?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04230213's enrollment target sits among peer trials
455 829th of 2000 higher than 1,170 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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