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NCT04228952 · ClinicalTrials.gov registry record
Metabolism of NNK in Japanese Americans
A clinical trial, sponsored by Masonic Cancer Center, University of Minnesota.
- Completed
- Registry status
- 16
- Enrollment target
NCT04228952 is a clinical trial that has completed, run by Masonic Cancer Center, University of Minnesota. The registered enrollment target is 16 participants.
The verdict
NCT04228952 has completed, sponsored by Masonic Cancer Center, University of Minnesota.
- COMPLETED
- Registry status
- 16 participants
- Enrollment target
Study Summary
The risk of lung cancer varies by individual and by ethnic/racial group. In this study the investigators will explore how individual differences in the metabolism of a tobacco-specific lung carcinogen may contribute to the variable risk of lung cancer between ethnic/racial groups. In this 10 day clinical trial, Japanese Americans will smoke a cigarette containing deuterium-labeled 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific lung carcinogen. The study cigarette will be smoked for 7 days. This will allow for NNK metabolic profiling and determining the effect of CYP2A6 genotype on the level of NNK α-hydroxylation in Japanese Americans smokers using \[pyridine- D4\]-NNK containing cigarettes.
Interventions
- COMBINATION_PRODUCT Modified Natural American Spirit-Tan or Green cigarettes injected with labeled NNK
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2020-09-01 |
| Est. Completion | 2025-04-14 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04228952
The ClinicalTrials.gov registry entry for NCT04228952 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Masonic Cancer Center, University of Minnesota, which has 249 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Modified Natural American Spirit-Tan or Green cigarettes injected with labeled NNK is the first listed.
NCT04228952 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04228952 about?
NCT04228952 is a clinical study titled "Metabolism of NNK in Japanese Americans". The risk of lung cancer varies by individual and by ethnic/racial group. In this study the investigators will explore how individual differences in the metabolism of a tobacco-specific lung carcinogen may contribute to the variable risk of lung cancer between ethnic/racial groups. In this 10 day cl...
What is the current status of trial NCT04228952?
This trial is currently completed. The enrollment target is 16 participants. The study started on 2020-09-01. Estimated completion is 2025-04-14.
What interventions are being tested in trial NCT04228952?
The interventions under investigation include: Modified Natural American Spirit-Tan or Green cigarettes injected with labeled NNK (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT04228952?
This trial is sponsored by Masonic Cancer Center, University of Minnesota, which has 249 total clinical trials registered on ClinicalTrials.gov.
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