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NCT04211545 · ClinicalTrials.gov registry record · Phase 1
Relative Bioavailability and PPI Effects of CC-92480 Test and Reference Formulations in Healthy Subjects
A Phase 1 study, sponsored by Celgene.
- Completed
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
NCT04211545: Completed Phase 1 study, sponsored by Celgene.
NCT04211545 is a Phase 1 study that has completed, run by Celgene. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04211545, a Phase 1 study, has completed, sponsored by Celgene.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
Study Summary
This is a Phase 1, open-label, randomized, four-period, crossover study in healthy females of nonchildbearing potential and male subjects - to be conducted at a single center in the United States. The study will consist of a screening phase, a baseline phase, four treatment periods, and a follow-up phone call. The 4 treatment periods are divided into two pairs (Period 1 and 2 and Period 3 and 4), potentially separated by an intermission during which subjects will be discharged from the research unit: Periods 1 and 2 support relative bioavailability (RBA) estimation, while Periods 3 and 4 support estimation of PPI effects.
Primary Outcome
Area under the plasma concentration-time curve from time zero to infinity
Interventions
- DRUG Rabeprazole
- DRUG CC-92480
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2019-10-21 |
| Est. Completion | 2019-12-26 |
| Phase | Phase 1 |
What the finished NCT04211545 record still lists
NCT04211545 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).
The record links to 0 conditions, and to 2 interventions - of which Rabeprazole is the first listed.
NCT04211545 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04211545 about?
NCT04211545 is a clinical study titled "Relative Bioavailability and PPI Effects of CC-92480 Test and Reference Formulations in Healthy Subjects". This is a Phase 1, open-label, randomized, four-period, crossover study in healthy females of nonchildbearing potential and male subjects - to be conducted at a single center in the United States. The study will consist of a screening phase, a baseline phase, four treatment periods, and a follow-up...
What is the current status of trial NCT04211545?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2019-10-21. Estimated completion is 2019-12-26.
What interventions are being tested in trial NCT04211545?
The interventions under investigation include: Rabeprazole (DRUG), CC-92480 (DRUG).
Who is sponsoring clinical trial NCT04211545?
This trial is sponsored by Celgene, which has 308 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04211545's enrollment target sits among peer trials
24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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