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NCT04210986 · ClinicalTrials.gov registry record · Phase 1

Senolytic Drugs Attenuate Osteoarthritis-Related Articular Cartilage Degeneration: A Clinical Trial

A Phase 1 study, sponsored by Steadman Philippon Research Institute.

Completed
Registry status
Phase 1
Development phase
75
Enrollment target

NCT04210986: Completed Phase 1 study, sponsored by Steadman Philippon Research Institute.

NCT04210986 is a Phase 1 study that has completed, run by Steadman Philippon Research Institute. The registered enrollment target is 75 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (25% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04210986, a Phase 1 study, has completed, sponsored by Steadman Philippon Research Institute.

COMPLETED
Registry status
Phase 1
Development phase
75 participants
Enrollment target

Study Summary

Phase I/II randomized, double-blind, placebo-controlled clinical trial to test the safety and efficacy of Fisetin for treating mild to moderate osteoarthritis

Primary Outcome

Number of Participants Experiencing one or more Treatment-Emergent Adverse Event (TEAE) within each group.

Interventions

  • DRUG Placebo oral capsule
  • DIETARY_SUPPLEMENT Fisetin

Trial Details

FieldValue
Enrollment Target 75 participants
Start Date 2020-01-06
Est. Completion 2023-02-01
Phase Phase 1

What the finished NCT04210986 record still lists

NCT04210986 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (25% higher).

The record links to 0 conditions, and to 2 interventions - of which Placebo oral capsule is the first listed.

NCT04210986 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04210986 about?

NCT04210986 is a clinical study titled "Senolytic Drugs Attenuate Osteoarthritis-Related Articular Cartilage Degeneration: A Clinical Trial". Phase I/II randomized, double-blind, placebo-controlled clinical trial to test the safety and efficacy of Fisetin for treating mild to moderate osteoarthritis

What is the current status of trial NCT04210986?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 75 participants. The study started on 2020-01-06. Estimated completion is 2023-02-01.

What interventions are being tested in trial NCT04210986?

The interventions under investigation include: Placebo oral capsule (DRUG), Fisetin (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT04210986?

This trial is sponsored by Steadman Philippon Research Institute, which has 7 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04210986's enrollment target sits among peer trials

75 711th of 2000 higher than 1,276 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04210986, the US trial registry maintained by the National Library of Medicine. NCT04210986 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.