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NCT04209725 · ClinicalTrials.gov registry record · Phase 2

A Study of CPX-351 (Vyxeos™) With Quizartinib for the Treatment of FLT3-ITD Mutation-Positive Acute Myeloid Leukemia

A Phase 2 study, sponsored by SCRI Development Innovations.

Terminated
Registry status
Phase 2
Development phase
1
Enrollment target

NCT04209725 is a Phase 2 study that was terminated before completion, run by SCRI Development Innovations. The registered enrollment target is 1 participants.

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The verdict

NCT04209725, a Phase 2 study, was terminated before completion, sponsored by SCRI Development Innovations.

TERMINATED
Registry status
Phase 2
Development phase
1 participants
Enrollment target

Study Summary

This is a research study to be done at multiple sites in participants with advanced acute myeloid leukemia (AML) that have a mutation in Fms-like tyrosine kinase-3 internal tandem duplications (FLT3-ITD). This study is to learn more about an investigational drug, quizartinib, being tested with the anti-cancer medicine CPX-351 (also called Vyxeos™), which is approved and widely used to treat AML. The purpose of this study is to assess the safety, tolerability and survival of patients receiving the combination of CPX-351 and quizartinib.

Interventions

  • DRUG Quizartinib
  • DRUG CPX-351

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2020-06-03
Est. Completion 2021-04-20
Phase Phase 2

Sponsor

SCRI Development Innovations

146 total trials

What the Registry Record Tells You About NCT04209725

The ClinicalTrials.gov registry entry for NCT04209725 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 1 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is SCRI Development Innovations, which has 146 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Quizartinib is the first listed.

NCT04209725 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04209725 about?

NCT04209725 is a clinical study titled "A Study of CPX-351 (Vyxeos™) With Quizartinib for the Treatment of FLT3-ITD Mutation-Positive Acute Myeloid Leukemia". This is a research study to be done at multiple sites in participants with advanced acute myeloid leukemia (AML) that have a mutation in Fms-like tyrosine kinase-3 internal tandem duplications (FLT3-ITD). This study is to learn more about an investigational drug, quizartinib, being tested with the a...

What is the current status of trial NCT04209725?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 1 participants. The study started on 2020-06-03. Estimated completion is 2021-04-20.

What interventions are being tested in trial NCT04209725?

The interventions under investigation include: Quizartinib (DRUG), CPX-351 (DRUG).

Who is sponsoring clinical trial NCT04209725?

This trial is sponsored by SCRI Development Innovations, which has 146 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.