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NCT04201418 · ClinicalTrials.gov registry record

A Multicenter Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation

A clinical trial of Polyneuropathy and Hereditary Transthyretin-mediated (ATTRv) Amyloidosis, sponsored by Alnylam Pharmaceuticals.

Completed
Registry status
67
Enrollment target
20
Study locations

NCT04201418 is a study of Polyneuropathy and Hereditary Transthyretin-mediated (ATTRv) Amyloidosis that has completed, run by Alnylam Pharmaceuticals. The registered enrollment target is 67 participants. The trial reports 20 study locations across 14 states.

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The verdict

NCT04201418, a study of Polyneuropathy and Hereditary Transthyretin-mediated (ATTRv) Amyloidosis, has completed, sponsored by Alnylam Pharmaceuticals.

COMPLETED
Registry status
67 participants
Enrollment target
20
Study locations

Study Summary

To evaluate the effectiveness of patisiran in patients with ATTRv amyloidosis with polyneuropathy who have a V122I or T60A mutation.

Interventions

  • DRUG Patisiran

Study Locations (20)

California

  • Clinical Trial Site - Los Angeles
  • Clinical Trial Site - San Diego

Florida

  • Clinical Trial Site - Jacksonville
  • Clinical Trial Site - Tampa

Georgia

  • Clinical Trial Site - Braselton
  • Clinical Trial Site - Macon

Illinois

  • Clinical Trial Site - Chicago
  • Clinical Trial Site - Chicago

North Carolina

  • Clinical Trial Site - Chapel Hill
  • Clinical Trial Site - Charlotte

Pennsylvania

  • Clinical Trial Site - Allentown
  • Clinical Trial Site - Bethlehem

Colorado

  • Clinical Trial Site - Aurora

Connecticut

  • Clinical Trial Site - Farmington

Trial Details

FieldValue
Enrollment Target 67 participants
Start Date 2019-12-18
Est. Completion 2022-05-24

Sponsor

Alnylam Pharmaceuticals

49 total trials

What the Registry Record Tells You About NCT04201418

The ClinicalTrials.gov registry entry for NCT04201418 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 67 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Alnylam Pharmaceuticals, which has 49 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Polyneuropathy appearing as the primary indexed condition, and to 1 intervention - of which Patisiran is the first listed.

NCT04201418 reports 20 study locations spanning 14 distinct geographic areas - top geographies include California, Florida, Georgia.

Frequently Asked Questions

What is clinical trial NCT04201418 about?

NCT04201418 is a clinical study titled "A Multicenter Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation". To evaluate the effectiveness of patisiran in patients with ATTRv amyloidosis with polyneuropathy who have a V122I or T60A mutation.

What is the current status of trial NCT04201418?

This trial is currently completed. The enrollment target is 67 participants. The study started on 2019-12-18. Estimated completion is 2022-05-24.

What conditions does trial NCT04201418 study?

This clinical trial studies the following conditions: Polyneuropathy, Hereditary Transthyretin-mediated (ATTRv) Amyloidosis.

What interventions are being tested in trial NCT04201418?

The interventions under investigation include: Patisiran (DRUG).

Who is sponsoring clinical trial NCT04201418?

This trial is sponsored by Alnylam Pharmaceuticals, which has 49 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04201418 being conducted?

This trial has 20 study locations across California, Colorado, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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