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NCT04200560 · ClinicalTrials.gov registry record · NA
Autophagy Maintains Vascular Function Through a Novel Glycolysis-linked Pathway Regulating eNOS
A NA study, sponsored by University of Utah.
- Completed
- Registry status
- NA
- Development phase
- 16
- Enrollment target
NCT04200560 is a NA study that has completed, run by University of Utah. The registered enrollment target is 16 participants.
The verdict
NCT04200560, a NA study, has completed, sponsored by University of Utah.
- COMPLETED
- Registry status
- NA
- Development phase
- 16 participants
- Enrollment target
Study Summary
Aging is inevitable and is the primary risk factor for developing cardiovascular disease. The molecular mechanisms that drive vascular dysfunction in the context of aging are incompletely understood. The overall hypothesis is that the age-related decline in endothelial cell (EC) autophagy leads to arterial dysfunction. This study will determine whether physiological shear-stress affects autophagosome formation and nitrous oxide (NO) generation in ECs.
Interventions
- OTHER Rhythmic Handgrip Exercise
- OTHER Chronic Exercise Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2018-07-01 |
| Est. Completion | 2022-05-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04200560
The ClinicalTrials.gov registry entry for NCT04200560 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Utah, which has 818 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Rhythmic Handgrip Exercise is the first listed.
NCT04200560 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04200560 about?
NCT04200560 is a clinical study titled "Autophagy Maintains Vascular Function Through a Novel Glycolysis-linked Pathway Regulating eNOS". Aging is inevitable and is the primary risk factor for developing cardiovascular disease. The molecular mechanisms that drive vascular dysfunction in the context of aging are incompletely understood. The overall hypothesis is that the age-related decline in endothelial cell (EC) autophagy leads to a...
What is the current status of trial NCT04200560?
This trial is currently completed. It is a NA study. The enrollment target is 16 participants. The study started on 2018-07-01. Estimated completion is 2022-05-30.
What interventions are being tested in trial NCT04200560?
The interventions under investigation include: Rhythmic Handgrip Exercise (OTHER), Chronic Exercise Training (OTHER).
Who is sponsoring clinical trial NCT04200560?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
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