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NCT04199351 · ClinicalTrials.gov registry record · Phase 1
Single and Multiple Ascending Dose Study of AMG 171 in Subjects With Obesity
A Phase 1 study, sponsored by Amgen.
- Terminated
- Registry status
- Phase 1
- Development phase
- 60
- Enrollment target
NCT04199351: Clinical Trial Phase 1 study, sponsored by Amgen.
NCT04199351 is a Phase 1 study that was terminated before completion, run by Amgen. The registered enrollment target is 60 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04199351, a Phase 1 study, was terminated before completion, sponsored by Amgen.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 60 participants
- Enrollment target
Study Summary
To assess the safety and tolerability of AMG 171 as single or multiple doses in subjects with obesity
Primary Outcome
An adverse event (AE) was any untoward medical occurrence in a clinical study participant irrespective of a causal relationship with study treatment. A serious AE (SAE) was an AE meeting at least 1 of the following serious criteria: fatal, life-threatening, required in-patient hospitalization or prolongation of existing hospitalization; resulted in persistent or significant disability; congenital anomaly/birth defect; other medically important serious event. Clinically significant changes from b
Interventions
- DRUG Placebo
- DRUG AMG 171
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2019-12-13 |
| Est. Completion | 2021-09-10 |
| Phase | Phase 1 |
Why NCT04199351 stopped before completion
NCT04199351 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04199351 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04199351 about?
NCT04199351 is a clinical study titled "Single and Multiple Ascending Dose Study of AMG 171 in Subjects With Obesity". To assess the safety and tolerability of AMG 171 as single or multiple doses in subjects with obesity
What is the current status of trial NCT04199351?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2019-12-13. Estimated completion is 2021-09-10.
What interventions are being tested in trial NCT04199351?
The interventions under investigation include: Placebo (DRUG), AMG 171 (DRUG).
Who is sponsoring clinical trial NCT04199351?
This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04199351's enrollment target sits among peer trials
60 831st of 2000 higher than 1,106 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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