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NCT04193202 · ClinicalTrials.gov registry record · Phase 3

Efficacy and Safety of Gefapixant (MK-7264) in Adult Participants With Recent Onset Chronic Cough (MK-7264-043)

A Phase 3 study, sponsored by Merck Sharp & Dohme.

Completed
Registry status
Phase 3
Development phase
419
Enrollment target

NCT04193202 is a Phase 3 study that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 419 participants.

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The verdict

NCT04193202, a Phase 3 study, has completed, sponsored by Merck Sharp & Dohme.

COMPLETED
Registry status
Phase 3
Development phase
419 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the efficacy and safety of gefapixant in participants with recent onset chronic cough (duration \>8 weeks after onset of cough symptoms) for \<12 months and a diagnosis of refractory or unexplained chronic cough. The primary hypothesis is that gefapixant is superior to placebo in improving cough-related quality of life measured as change from baseline in the Leicester Cough Questionnaire (LCQ) total score at Week 12.

Interventions

  • DRUG Placebo
  • DRUG Gefapixant

Trial Details

FieldValue
Enrollment Target 419 participants
Start Date 2020-05-21
Est. Completion 2021-11-03
Phase Phase 3

Sponsor

Merck Sharp & Dohme

558 total trials

What the Registry Record Tells You About NCT04193202

The ClinicalTrials.gov registry entry for NCT04193202 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 419 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Merck Sharp & Dohme, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04193202 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04193202 about?

NCT04193202 is a clinical study titled "Efficacy and Safety of Gefapixant (MK-7264) in Adult Participants With Recent Onset Chronic Cough (MK-7264-043)". The purpose of this study is to evaluate the efficacy and safety of gefapixant in participants with recent onset chronic cough (duration \>8 weeks after onset of cough symptoms) for \<12 months and a diagnosis of refractory or unexplained chronic cough. The primary hypothesis is that gefapixant is s...

What is the current status of trial NCT04193202?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 419 participants. The study started on 2020-05-21. Estimated completion is 2021-11-03.

What interventions are being tested in trial NCT04193202?

The interventions under investigation include: Placebo (DRUG), Gefapixant (DRUG).

Who is sponsoring clinical trial NCT04193202?

This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.